Yet despite the widespread use of organic trace minerals (OTMs), one important misconception continues to exist in the industry: that all organic trace minerals are the same.

Looking Beyond Inclusion Levels
When evaluating trace mineral programs, discussions often focus on inclusion rates, mineral concentration, and cost per ton of feed.

However, the true value of a trace mineral is not determined simply by how much is added to a formulation. Rather, it is determined by how much of that mineral is available for absorption and utilization by the bird. This distinction becomes increasingly important in modern poultry production.

Many producers experiencing challenges like, inconsistent performance, reduced meat quality, or variability in the flock focus on nutrient inclusion. Yet nutrients can only contribute to biological functions if they successfully reach the absorption sites where they are needed.

As poultry genetics continue to advance, nutritional efficiency has become just as important as nutritional adequacy. This shift is causing nutritionists to move beyond a simple question of: “How much mineral is in the feed?” to a more important question: “How much mineral is actually available to the bird?”

Understanding the Challenge: Mineral Antagonism
Trace minerals perform important functions throughout the bird’s body. Zinc, copper, and manganese act as cofactors for numerous enzymes involved in bone formation, connective tissue development, collagen synthesis, skin integrity, antioxidant defense, and immune function.

However, the digestive tract is a highly complex environment. As minerals move through digestion, they encounter changes in pH and interactions with dietary compounds such as phytate, fiber components, and even other minerals. These interactions can reduce mineral availability before absorption occurs.

This phenomenon, referred to as mineral antagonism, helps explain why increasing mineral inclusion does not always result in improved mineral utilization. Simply feeding more minerals does not necessarily mean the bird receives more minerals. In many situations, the challenge is not supply. The challenge is bioavailability.

Dietary antagonisms can reduce mineral availability before absorption occurs, limiting nutrient utilization despite adequate inclusion levels

Organic Trace Minerals: A Category, Not a Chemistry
To help improve mineral bio-availability, the industry increasingly adopted organic trace minerals. However, the term “organic trace mineral” can create confusion. Some assume that all OTMs provide similar benefits because they belong to the same category. In reality, organic trace minerals represent a broad group of products that may differ substantially in:
· Ligand type
· Ligand-to-mineral ratio
· Molecular structure
· Bonding characteristics
· Electrical charge of the molecule
· Stability in Upper Digestive Tract
These differences influence how minerals behave in the gastrointestinal tract and how effectively they remain available for absorption. In other words, two products may both be labelled as organic trace minerals while functioning very differently inside the bird.

Why Chelation Matters
Among organic trace minerals, one class stands out from the others: bis-chelates. The word chelate originates from the Greek word chela, meaning crab claw or pincer. Similar to two crabs holding a metal securely giving it the maximum protection a Chelate forms when a ligand connects to a metal atom at more than two points. A 2 five member rings connected to the metal with two points of contact is the most stable complex found in nature. This structure helps provide protection compared with less defined mineral associations. However, not all organic trace minerals are true chelates. True chelates require a neutral charge to protect the mineral and enhance stability. Not all organic trace minerals (OTMs) provide a neutral charge; therefore, not all OTMs are true chelates. Some products are better described as complexes, proteinates, or other association forms. While they are still classified as organic trace minerals, they can differ significantly in chemical stability and behavior during digestion. The degree of protection provided by the mineral structure ultimately determines how vulnerable the mineral may be to antagonistic interactions.
Differences exist among chelates, too. There are chelates where one ligand is bound to the metal and then there are bis-chelates where two ligands are bound, creating a neutral charge and making the molecule less susceptible to antagonism. (see image)

Why Molecular Structure Matters
Research continues to demonstrate that mineral structure influences stability and bio-availability. When minerals dissociate during digestion, they become charged ions that are more likely to interact with negatively charged compounds such as phytate, fiber complexes and other minerals. These interactions can reduce availability before absorption occurs.

For this reason, increasing attention is being given to mineral structures specifically designed to maintain stability throughout digestion. One such approach is bis-chelation technology.

Bis-chelated trace minerals are characterized by a defined molecular structure consisting of one mineral ion bound to two ligands, creating two stable chelate rings. This unique architecture helps maintain structural integrity while moving through the digestive tract.
An equally important feature is their neutral molecular charge. Because neutrally charged molecules are less likely to participate in unwanted interactions, the structure helps protect the mineral, reducing opportunities for antagonism and supporting mineral availability until absorption occurs.

Bis-chelated trace minerals feature a defined molecular structure designed to support stability and mineral availability during digestion.

The Future of Trace Mineral Nutrition
As poultry production evolves, mineral nutrition must evolve with it. The industry’s next opportunity may not come from increasing mineral inclusion rates but from improving how effectively minerals are utilized by the bird. This requires looking beyond product categories and focusing on the scientific characteristics that influence mineral availability. Organic trace minerals can provide significant advantages over traditional inorganic sources. However, not all organic trace minerals are created equal. Their molecular structure matters. Their stability matters. And ultimately, their ability to deliver minerals to the animal matters.

As nutritionists continue searching for ways to improve performance consistency, skeletal integrity, meat quality, and return on investment, bis-chelated trace minerals are an increasingly important technology because they combine defined structure, enhanced stability, and optimized bioavailability into a scientifically designed mineral solution.

Contact your local NOVUS representative to learn more about bis-chelated trace minerals from the company that brought the technology to the animal agriculture industry over 20 years ago.

Dr. Partha P. Biswas, Former Associate Professor & HoD,

Because more poultry meat and eggs are being produced worldwide, people are asking for better, more sustainable ways to farm. This means finding new and better ways to feed animals in the future. From 2000 to 2020, global egg production went up by more than 41%, increasing from 51 million to 87 million tonnes, with an average annual growth rate of 3%.In 2023, poultry meat production hit 145 million tonnes and is still rising. With 6.29 million tonnes produced in 2020, India is fast approaching the level of production in the USA (6.29 million tonnes) produced in 2020. With an average egg size slightly lower than that in the USA (average weight of a standard large chicken egg 56.7 grams (2 oz) in the USA as against 50 to 55 grams in India), the Indian egg sector estimated that they have already overtaken the USA in terms of the number of eggs produced. India produced 149.11 billion eggs in the 2024–25 period, while the United States produced approximately 105 billion eggs in 2025. This growth is making it more important to find sustainable ways to feed animals.Even though raising poultry is less harmful to the environment compared to other types of animal farming, it still has some negative effects, such as increasing global warming, making water too rich in nutrients (eutrophication), and making soil too acidic. Low-carbon poultry feed is now moving from just an idea to real, practical use. Feed is responsible for about 70% of the total carbon footprint in poultry farming, so it’s the biggest area where we can cut down on carbon emissions. To make poultry farming more sustainable, we need to change how we get, mix, and use feed. Soybean meal and fishmeal have been the main sources of protein for animals, used in everything from chicken farming to fish farming. But keeping on using them at the same levels is bad for the environment. The reason we’re looking for alternatives isn’t because these materials don’t work well for animals—they are very effective. It’s because they cause serious environmental and economic problems, especially for systems that try to be sustainable and manage fish resources properly.

CIRCULAR AND ALTERNATIVE INGREDIENTS
Producers are actively moving away from relying entirely on conventional corn and deforestation-linked soy. Feed formulations are increasingly incorporating agro-industrial by-products, former foodstuffs (circular feed), and alternative protein crops like rapeseed and peas.
Life Cycle Assessments show that feeds formulated with these by-products can have a carbon footprint nearly 40% lower than traditional raw material feeds.

THE “BIG THREE INGREDIENTS” OF POULTRY FEED
Poultry sector consumes ~60% of India’s maize (~20+ million tonnes annually).Soybean meal demand: ~6-7 million tonnes domestically. In commercial broiler and layer operations, dry fish meal is rarely used When added at strategic levels, typically 3-8% in starter feeds and 2-5% in grower phases, fish meal enhances palatability, encouraging birds to consume more feed during critical early stages. This increased intake, paired with high digestibility, results in superior weight gains and improved FCR. In the layer segment, specialized demand exists for producing enriched eggs. The long-chain n-3 fatty acids (like DHA) in marine lipids transfer efficiently into the yolk.

1. SOYBEAN MEAL (THE PROTEIN BASE) : Soybean meal is the main source of protein in chicken feed around the world, but it has a big impact on the environment. The protein in soybean meal is high in lysine, which is first limiting amino acid in most chicken diets. This makes it a great match for grains like corn and wheat. India does not allow growing or bringing in raw genetically modified (GM)soybeans or seeds. India’s soybean production fell a lot during the 2025-2026 growing season, reaching about 11 to 12.7 million tons, which is much lower than before, causing a serious shortage of supply. When there are not enough non-GM soybeans locally, they get them from certain African countries. Non-GM soybeans are more expensive than GM ones. Even though GM soybean meal has been allowed sometimes to meet the protein needs for animal feed, there are worries about the effects on the environment. These worries include carbon emissions from cutting down forests in important areas like the Amazon and Cerrado, more risks for climate change, loss of wildlife, and pollution from farm chemicals running into water.

2.CORN / MAIZE (THE ENERGY SOURCE) : Corn provides the bulk energy in most poultry diets. While corn generally has a lower carbon footprint per kilogram than soy, birds eat much more of it. The primary carbon issue with corn is its heavy reliance on synthetic nitrogen fertilizers. Manufacturing these fertilizers is extremely energy-intensive, and applying them to fields releases nitrous oxide (N₂O),a green house gas nearly 300 times more potent than carbon dioxide. Tractor fuel for plowing is another important issue.

3.FISH MEAL (THE SPECIALITY PROTEIN) : Though used in far smaller amounts (typically for young chicks or breeder birds), fish meal has a complex environmental footprint. The issue of TMA accumulation leading to a fishy flavor in brown-shelled eggs arises from a genetic defect in up to 10% of brown-feathered hens. Normally, TMA is oxidized in the liver into a harmless compound by the action of the enzyme trimethylamine oxidase. The synthesis of this enzyme depends on the expression of the FM03 gene, located on chromosome 8. In the case of anon-synonymous mutation in the FM03 gene (designated T3295),hens cannot oxidize TMA, which then accumulates in the yolk. Poultry diets restrict fish meal to 5-10% of total feed due to ecological inefficiencies. Fishmeal is sourced from small forage fish like anchovies and sardines, which are crucial to the marine food web. Overfishing these species endangers higher trophic levels, leading to decline predatory fish, marine mammals, and seabirds.Moreover, forage fish populations are vulnerable to climate change, causing unstable fishmeal supplies and significant price volatility.India is the third-largest producer and exporter of fishmeal. Fig.1:

Fig.1: Typical poultry feed mix

ECONOMIC HURDLES TO TRANSITION OF CIRCULAR PROTEINS
The transition to circular proteins, such as microbial biomass, insect meal, or fermented agro-industrial waste, is essential for stabilizing ecosystems and is crucial for a sustainable livestock industry. However, commercial feed mills face significant economic barriers due to scale, commodity pricing, and supply chain maturity, making it challenging to replace traditional soybean meal. Here are the primary economic hurdles commercial mills face today:

THE PRICE PARITY GAP
Decades of agricultural subsidies, optimized supply chains, and massive economies of scale keep their prices relatively low and stable (historically ranging from $600-$750 per ton for soy, and $1,500 to $2,000 for fishmeal). In contrast, alternative proteins like Black Soldier Fly Larvae (BSFL) or microalgae carry immense initial capital expenditures (CapEx) to build high-tech bio-manufacturing or fermentation facilities.
Although insects like Black Soldier Fly Larvae (BSFL) raised on organic waste represent the ultimate circular protein, converting low-value biomass into high-value feed with a minimal land and water footprint. BSFL defatted protein meal and de-oiled powder generally trade between ₹110 and ₹250 per kg in Indian market & wholesale price roughly between $1,320 and $3,000 USD per ton.

SCALE AND VOLUME CONSISTENCY
Commercial feed mills produce feed continuously, requiring tens of thousands of tons of standardized ingredients every single month. Currently, very few alternative protein manufacturers can guarantee that volume without interruption. If a mill alters its highly specific formulation to include 5% insect meal, and the supplier falls short on delivery, the mill has to halt production, re-calibrate its software, and reformulate the diet using different ingredients. This downtime is extraordinarily expensive.

HIDDEN COSTS OF NUTRITIONAL REBALANCING
Soybean meal and fishmeal are highly dependable. Nutritionists have a clear understanding of how these ingredients function within the digestive systems of fish and birds. When a mill uses insect meal or a plant-based alternative to fishmeal, the amino acid profile changes. As a result, the mill needs to purchase additional synthetic amino acids, such as L-methionine or L-lysine, along with specific feed enzymes to compensate for the missing nutrients. This helps maintain the animals’ growth rates. Even if the base alternative protein is priced competitively, these added ingredients increase the overall cost of the final feed formulation.

RETROFITTING MILL INFRASTRUCTURE
Feed mills are designed to handle, grind, and pellet traditional grains and meals. However, alternative ingredients often have very different physical properties. For instance, some insect meals contain significantly more fat than solvent-extracted soybean meal. High levels of lipids can cause blockages in extruders, reduce the quality of feed pellets (making them prone to breaking during transport), and damage machinery. To effectively use these new ingredients at high levels, mills usually need to invest heavily in upgrading their equipment, such as adding new vacuum liquid-coating systems for fats. Many mills are reluctant to make these costly investments due to financial concerns.

REGULATORY APPROVAL COSTS
The global feed industry has strict rules to stop harmful substances from getting into the food chain. To get approval for a new type of protein, like microbial biomass or insect protein, used in animal feed, companies must do many expensive and time-consuming tests. These tests check for safety, look for heavy metals, and measure how well the protein is digested. This process can take many years.The cost of these tests ends up being passed on to the feed producers, which raises the cost of the ingredients. Unless these alternative proteins can be made in large amounts and sold at prices that are as good as soy or wild-caught fish, they are probably only used in special, high-end, or environmentally friendly feed products, not in regular, mass-produced feeds..Fig.2:

Fig.2: A picture showing how to raise chickens in a way that is good for the environment, people, and the poultry industry. It shows how being efficient with resources, taking care of the chickens’ health and happiness, keeping the farm safe from disease, making sure the chickens are productive, and making the whole food system strong and able to handle challenges are all connected and important.

THE GLOBAL RACE TO DECARBONIZE LIVESTOCK DIET

CIRCULAR INGREDIENTS & CARBON REDUCTION
Upcycling Waste: Using agricultural and slaughterhouse by-products (like DDGS, fruit pomace, and rendered fats) reduces reliance on land-intensive virgin crops and prevents landfill methane. The sustainable use of fruit and vegetable residues (FVRs) in poultry feed formulations has gained considerable attention due to their potential in advancing animal health However, certain challenge such as anti-nutritional factors, palatability issues, and processing techniques are also associated while incorporating these residues into poultry diets. Fermentation technologies create new opportunities to recover nutrients from agricultural residues and improve their value in poultry diets.

Carbon-Optimized Formulation: Modern feed software integrates Life Cycle Assessment (LCA) data to dynamically select ingredients based on their carbon footprint, not just cost and nutrition. LCA is a measurement of the emissions generated during its cultivation, processing, and transport. The software can calculate the exact environmental cost of using raw protein crops (like soy) versus supplementing with synthetic amino acids. It optimizes the diet to prevent protein overfeeding, which simultaneously lowers the feed’s initial GWP (Global Warming Potential) and reduces the nitrogen output (and offensive odors) in the poultry droppings.

THE SHIFT TO DDGS (DISTILLERS DRIED GRAINS WITH SOLUBLES)

Cost Advantage: Maize-based DDGS (₹17-₹20/kg) is significantly cheaper than soymeal (~₹40/kg), driving rapid adoption in the poultry industry.
Substitution Limits: DDGS can replace 25-30% of maize demand. Insect protein and algae can replace small portions of soy (5-10%).
Ongoing Conventional Reliance: Despite these alternatives, conventional ingredients will still make up 60-70% of overall feed requirements.
PRECISION NUTRITION
Targeted Diets: Formulating feed to match exact amino acid and energy needs improves the Feed Conversion Ratio (FCR).
Lower Emissions: Preventing protein overfeeding reduces nitrogen in manure, which directly lowers harmful nitrous oxide (N₂O) emissions downstream. Fig.3

Fig.3: Alternative protein sources for animal feed in a circular bioeconomy could include things like leftover materials from farming and food processing, meals made from insects and worms, leftovers from biorefineries, proteins made by microbes, and by-products from aquatic sources.

BETWEEN REALITY AND RHETORIC: LOW-CARBON POULTRY FEED
Moving from using a wide variety of ingredients in poultry feed to providing exactly what the birds need at each stage of growth is key to creating real low-carbon feed. While some talk about replacing soy with new ingredients, the actual science is about making tiny, precise changes. It’s about giving birds exactly the right nutrients they need, in the right amounts, so nothing is wasted. Real reductions in carbon emissions from poultry feed don’t come from using popular or fashionable ingredients. They come from making sure every part of the feed works as efficiently as possible. Ensuring every gram of feed is used well is the best way a farm can help the environment. Instead of providing too much crude protein, experts can use specific synthetic amino acids like L-Methionine, L-Lysine, and L-Threonine.This helps reduce the total amount of crude protein in the birds’ diets. By cutting crude protein by just 1.5%, farms can lower their carbon footprint by about 70 kg of CO₂ equivalent per ton.

CONCLUSION
Despite having significant potential, incorporating insects, algae, fermented products, and agricultural and industrial by-products into chicken feed continues to face multiple challenges. These challenges include scientific, technical, economic, and legal difficulties. For insects, key issues include variability in their nutritional content based on their diet, high chitin content that complicates protein digestion for chickens, higher production costs compared to traditional protein sources, and the absence of established international safety and quality standards. Consumer acceptance of chicken products derived from insect-based diets remains uncertain, which may hinder large-scale adoption. The effort to reduce the carbon footprint in chicken feed presents a mix of real benefits and exaggerated claims. While some measurable progress is achievable, the extent and impact of these improvements often fall short of what companies assert. Reducing the carbon footprint in chicken feed is neither a complete solution nor a total myth; it represents incremental steps within a broader system that is not sustainable. The true advantages come from the following areas:

– Integrating a circular bioeconomy into feed production
– Minimizing reliance on imported protein
– Utilizing waste materials effectively
– Developing better alternative ingredients

The industry must shift from making grand promises to achieving tangible improvements. This involves recognizing and celebrating small achievements, such as 5-10% reductions, while also being honest about limitations and working towards broader changes that extend beyond mere feed modifications. This conclusion reflects both the actual progress being made and the gap between marketing claims and real-world outcomes, offering a balanced assessment of the industry’s current position regarding sustainable feed promises. Hybrid feeding systems that combine commercial and alternative feed sources generally provide the most consistent results, although maintaining mineral balance is essential during the laying phase.

REFERENCES
1.Vincent Guyonnet (2025) : Chapter 2 World Egg Production and Marketing Trends, In book: Handbook of egg science and technology (pp.9-26) Publisher: CRC Press. DOI:10.1201/9781003254430-3.
2.Hairui Yu et al (2025): Sustainable poultry farming: mitigation of greenhouse gas emissions in poultry farming through nutritional and environmental modulations. World’s Poultry Science JournalVolume 81, 2025 – Issue 4: Pages 1081-1141.
3.Dheeraj Kumar et al (2025): Alternative feed ingredients in poultry diets: A review of nutritional potential, processing technologies, and challenges. International Journal of Veterinary Sciences and Animal Husbandry 2025; SP-10(9): 16-19.
4.Yadi Oktariansyah*& Mustafa Kamal (2026): Alternative Feed Use in Poultry Chickens: Impacts on Feed Efficiency and Physiological Parameters—A Systematic Literature Review. Journal of Natural Sciences ISSN 2721-5571 (Online) Vol.7, No.1 March 2026: 41-53.

The 10th edition of the Global Talks Series features an insightful conversation with Mr. Franck Vaillant, Commercial Director at IDENA, a renowned French company specializing in animal nutrition and feed additive solutions. With more than 30 years of experience in the animal production industry, Franck Vaillant has been actively involved in international business development across global markets. Throughout his professional journey, he has focused on advancing science-based nutritional solutions that support animal health, performance, and sustainable livestock production. In this edition, he shares his perspectives on the evolving global poultry industry, including key challenges such as antibiotic reduction, gut health management, feed efficiency, and sustainability. He also discusses how IDENA is helping poultry producers through innovative nutritional strategies designed to improve bird resilience and production performance under modern commercial farming conditions. The discussion further highlights the growing potential of the Indian poultry industry and the increasing demand for natural and functional feed additive solutions in the years ahead.

Career Journey in Animal Nutrition
Franck Vaillant is currently Commercial Director at IDENA, a position he has held since 2023. Prior to this, he served for 12 years as Managing Director of a French animal nutrition company specialized in feed supplements. He began his career in the animal production sector in 1994. Throughout his professional journey, he has focused on driving international business development across all continents.

IDENA’s Vision for Poultry Nutrition
IDENA’s core vision is to support animal production through science-based nutrition while actively contributing to demedication in livestock. Our main focus is to provide natural and functional alternatives to traditional medicinal approaches, helping producers maintain performance through nutrition rather than treatment. In poultry, we focus on gut health, mineral balance, feed efficiency, and resilience of birds under commercial conditions. Our solutions combine R&D, field validation, and practical formulation expertise to ensure both technical efficiency and economic viability.

Global Poultry Industry Trends and Challenges
According to Franck Vaillant, the poultry industry is currently shaped by strong pressure on antibiotic reduction, feed cost volatility, and increasing genetic potential of birds. One of the major challenges is maintaining gut stability and performance in a context of reduced medication use. This drives a global shift toward preventive nutrition, functional additives, and precision feeding strategies that improve nutrient efficiency and animal robustness.

Supporting Sustainability and Antibiotic Reduction
Sustainability, gut health, and reduced antibiotic use are central pillars of IDENA’s nutritional approach.
The company develops feed additive solutions that support intestinal health, microbial balance, digestion efficiency, and oxidative stress management, helping poultry producers reduce their reliance on antibiotics while maintaining productivity.

IDENA’s solutions are backed by extensive R&D, laboratory studies, in vivo trials, and field validations conducted under different farming conditions worldwide. In addition, the company works on optimizing mineral and nutrient utilization to reduce environmental impact and improve sustainability at the farm level.

“The future of poultry production will
depend on our ability to combine
performance, sustainability,
and reduced medication use through
science-based nutrition and
innovative feed solutions.”

— Franck Vaillant, IDENA

Perspective on the Indian Poultry Industry
Franck Vaillant views India as one of the world’s fastest-growing poultry markets, driven by rising demand for affordable animal protein and rapid industry modernization. At the same time, he recognizes that the Indian market remains highly competitive and price-sensitive, requiring nutritional solutions that deliver both technical performance and strong economic returns.

He believes there are significant future opportunities for IDENA in India, particularly in supporting poultry producers with natural feed additive solutions focused on gut health improvement, feed efficiency optimization, and reduced medication use under local production conditions.

FERMNUTRAL: A POSTBIOTIC INNOVATION TO MAXIMIZE GUT HEALTH AND EFFICIENCY IN POULTRY PRODUCTION

Gut Health: The Key to Modern Poultry Production
The expression of the genetic potential of poultry largely depends on intestinal health. The gastrointestinal tract houses nearly 70% of the immune cells and constitutes the primary barrier against enteric pathogens. However, during the early stages of life, immune immaturity increases susceptibility to infections and microbiota imbalances, particularly under intensive production systems.

Traditionally, antibiotic growth promoters (AGPs) have been used to improve productive performance and reduce health-related challenges. However, their continuous use has been associated with antimicrobial resistance, intestinal dysbiosis, and concerns regarding food safety and public health.

In this context, postbiotics have emerged as a sustainable alternative. They are defined as preparations of inanimate microorganisms and/or their bioactive components, including short-chain fatty acids, bacteriocins, exopolysaccharides, peptides, and cell

wall fragments. Unlike probiotics, postbiotics offer greater stability, safety, and consistency, making them an effective alternative to AGPs (Zhong et al., 2022).

Postbiotics vs. Probiotics: A Real Competitive Advantage
The probiotics most commonly used in poultry production, such as Lactobacillus spp. and spore-forming Bacillus spp., present certain limitations when compared with postbiotics.

Lactobacillus species are heat-sensitive microorganisms; therefore, their survival during feed pelleting and storage may be compromised. In addition, factors such as chlorination of drinking water can reduce their viability and, consequently, their biological efficacy.

In contrast, Bacillus spp. exhibit high resistance to elevated temperatures due to spore formation. However, their beneficial effects may depend on successful intestinal germination and on the physiological and microbiological conditions of the host. Furthermore, these bacteria do not permanently colonize the gastrointestinal tract, meaning that their biological impact may depend on continuous administration through feed or drinking water.

Postbiotics exhibit high stability during feed processing and storage, as well as in chlorinated drinking water, because they do not rely on cell viability. Moreover, their bioactive compounds can exert their effects immediately upon ingestion, without requiring germination or intestinal colonization. This allows for a faster, more reproducible, and more consistent response (De Marco et al., 2018).

FermNutral: Bioactive Profile of a Full-Spectrum Postbiotic
FermNutral is a postbiotic developed and manufactured by CPBIO through the controlled biological fermentation of the Clostridium butyricum CPBIO3000 strain using natural raw materials. (Figure1)

The product is supplied as granules with demonstrated stability at temperatures exceeding 80°C (simulating the feed pelleting process). The recommended inclusion rate for poultry is 300–500 g/t of feed. FermNutral is produced under FAMI-QS, FDA-cGMP, and ISO 9001/14001/18001 certifications, which have been maintained since 2001.

FermNutral contains a diverse range of bioactive compounds generated during the fermentation process, including teichoic acids, lipoteichoic acids, butyricin, antimicrobial peptides, and exopolysaccharides.

Within its short-chain fatty acid (SCFA) fraction, butyric acid represents approximately 40% of the total SCFAs. Other SCFAs are present at lower concentrations, including acetic acid (21.6 mg/kg) and propionic acid (81.6 mg/kg).
The vitamin fraction includes vitamin E (13.9 IU/kg), vitamin B1 (17.2 mg/kg), vitamin B2 (5.08 mg/kg), vitamin B5 (57.3 mg/kg), vitamin B6 (98.3 mg/kg), vitamin B12 (0.34 mg/kg), folic acid (30.9 mg/kg), and vitamin K3 (1.97 mg/kg). The mineral profile provides calcium (15.2%), total phosphorus (0.76%), iron (760 mg/kg), zinc (42 mg/kg), magnesium (3,600 mg/kg), and chromium (11.67 mg/kg). Additionally, FermNutral contains 17 amino acids, including glutamic acid (1.37%), alanine (0.59%), valine (0.46%), leucine (0.50%), and lysine (0.29%). Altogether all amino acids are between 10-12% in product.

This unique combination of bioactive metabolites, nutrients, vitamins, minerals, and amino acids supports intestinal integrity, microbial balance, immune function, and productive performance in poultry.

Figure 1: A postbiotic product derived from biological fermentation of Clostridium butyricum CPBIO3000 using natural raw materials

FermNutral: Bioactive Compounds
FermNutral contains a wide range of bioactive compounds generated during the fermentation process, with butyric acid being the predominant short-chain fatty acid (SCFA), representing approximately 40% of the product. Butyrate serves as a major energy source for enterocytes and promotes epithelial renewal, mucin synthesis, and the expression of tight junction proteins. These effects contribute to maintaining intestinal barrier integrity and reducing intestinal permeability.
In addition, butyrate exhibits immunomodulatory and anti-inflammatory properties through its ability to regulate epigenetic processes, promote goblet cell differentiation, and stimulate the activation of regulatory T lymphocytes. It may also enhance intestinal serotonin release, which has been associated with the gut-brain axis and productive performance. Acetic and propionic acids complement these effects by regulating the intestinal environment and inhibiting undesirable microorganisms.

FermNutral also provides teichoic acids and lipoteichoic acids, which are recognized by Toll-like receptor 2 (TLR-2) on the intestinal mucosa. These components modulate both innate and adaptive immune responses, promoting a balance between immune defense and tolerance while helping to control intestinal inflammation (Pasquina et al., 2013; Muhammad et al., 2021).

Furthermore, FermNutral supplies butyricin (a bacteriocin), bioactive peptides, and antimicrobial peptides produced during fermentation, which contribute to the control of undesirable microorganisms and the modulation of intestinal microbiota. Exopolysaccharides are also present and have been reported to stimulate secretory IgA production and strengthen the mucosal barrier. In addition, the product’s vitamin and mineral profile acts synergistically to support immune function, antioxidant status, intestinal integrity, and productive performance.

FermNutral in poultry production
Several experiments conducted in China and Thailand have demonstrated the efficacy of FermNutral in poultry production. In a study at Guizhou University (China) comparing a control diet with additives such as FermNutral, Clostridium butyricum, protected sodium butyrate, and tributyrin in broiler chickens, the postbiotic (FermNutral) was confirmed to improve weight gain (+13%) and reduce feed conversion ratio (-11.68%) compared with the control and other experimental treatments.

In addition, another experiment carried out in a commercial broiler farm in China found that FermNutral reduced the feed conversion ratio (1.73 vs 1.77) and improved viability (+1.94) and the European Production Efficiency Factor (EPEF; 338.70 vs 315.30) in relation to the control diet.
Likewise, in a commercial broiler farm in Thailand, the use of FermNutral increased weight gain (+4.2%) and EPEF (+11.70%) and reduced feed conversion ratio (-7.69%). Furthermore, other trials conducted at Guizhou University (China) showed that FermNutral increased villus height in the duodenum (+9%), jejunum (+4%), and ileum (+8%), and improved the villus height to crypt depth ratio (V/C) in the duodenum (6.92 vs 6.27) and jejunum (5.71 vs 5.04).

Figure 3 : FermNutral effect on Immunoglobulins

Additional results from this experiment reported that FermNutral decreased the population of Escherichia coli in the duodenum (0.014 vs 0.234) and jejunum (0.0004 vs 0.013). Moreover, it promoted the growth of Lactobacillus in different intestinal segments, as determined by the relative abundance of microorganisms through 16S rDNA sequencing. (Figure 2) Finally, the inclusion of FermNutral in the diet improved the concentration of IgA (+13%), IgG (+19%), and IgM (+24%) compared with the control diet. (Figure 3)

Figure 2 : 16S rDNA sequencing to determine relative abundance of microorganisms in Poultry Intestine

Other trials conducted on a commercial farm in China with 48-week-old laying hens showed that FermNutral improved laying rate (+1.4) and shell thickness (+0.05 mm), while reducing feed conversion ratio (-0.06) and broken eggs (-2.6%), without affecting other productive performance parameters.

Likewise, in an experiment carried out at Henan Agricultural University, China, using 50-week-old laying hens, FermNutral increased egg weight (61.63 vs 59.77 vs g) and improved feed conversion ratio (2.08 vs 2.11 vs), while reducing dirty eggs (0.17 vs 0.45 %), broken eggs (0.32 vs 0.47 %), and unfit eggs (0.15 vs 0.28 %). These results demonstrate that FermNutral is an innovative and differentiated alternative within the new generation of postbiotics.

References
De Marco S, et al. (2018). Probiotic cell-free supernatants exhibit anti-inflammatory and antioxidant activity. Evidence-Based Complementary and Alternative Medicine.
Liu H, et al. (2023). Postbiotics modulate gut health and laying performance in laying hens. Animal Nutrition, 14, 244–256.
Muhammad I, et al. (2021). Lipoteichoic acid from Bacillus subtilis improves immune function of broiler chickens. Antioxidants, 10(9), 1414.
Pasquina LW, et al. (2013). Teichoic acid biosynthesis as an antibiotic target. Current Opinion in Microbiology, 16(5), 531–537.
Zhong R, et al. (2022). Gut microbiota and its interactions with postbiotics in animal production. Frontiers in Microbiology, 13, 831495.
About CPBIO – A Global Biotech Company, Based on the global practice of Charoen Pokphand Group in the agricultural, animal husbandry and food industry chain, CPBIO has extensively and deeply participated in the health cause of animals, the earth and human beings with the thinking of the whole industry chain. Organizations and individuals in large-scale validated products and solutions.

About CPBIO – A Global Biotech Company, Based on the global practice of Charoen Pokphand Group in the agricultural, animal husbandry and food industry chain, CPBIO has extensively and deeply participated in the health cause of animals, the earth and human beings with the thinking of the whole industry chain. Organizations and individuals in large-scale validated products and solutions.

Every day, a broiler’s intestine processes several times its body weight in feed and water, encounters billions of microorganisms, responds to environmental stress, and continuously decides what enters the body and what remains outside.

In many ways, the gut functions as a customs checkpoint, security system, digestive factory, and immune headquarters—all at the same time.

In fact, nearly 70% of the bird’s immune cells are associated with the gastrointestinal tract, making it a key player in both health and performance. The remarkable aspect is that when the gut is functioning well, nobody notices it. When it begins to fail, everybody notices the consequences.

The Modern Poultry Bird: Built for Speed
Today’s broiler is a biological marvel. Through decades of genetic selection, modern birds reach market weight faster and more efficiently than ever before.
However, this achievement comes with a hidden challenge.

The digestive tract has become one of the most critical performance-limiting organs in poultry production. Every gram of feed must be digested, absorbed, and converted into muscle within an increasingly compressed production cycle.

Twenty years ago, a small reduction in nutrient absorption might have gone unnoticed. Today, even minor intestinal inefficiencies can translate into measurable losses in body weight gain, feed conversion ratio, and profitability. Modern birds can no longer afford a lazy gut.

The Gut Is Constantly Making Decisions
Traditionally, we think of the intestine as a nutrient absorption organ.
In reality, the gut is making thousands of biological decisions every second.

– Should nutrients support growth or immunity?
– Should a microorganism be tolerated or eliminated?
– Should energy be invested in production or defense?
– Should the intestinal barrier remain open for absorption or tighten to prevent invasion?

These microscopic decisions ultimately determine flock performance.
In many ways, poultry production is not simply about feeding birds—it is about influencing the decisions being made within the gut.

The Hidden Cost of Inflammation
One of the most important concepts emerging in poultry science is that inflammation carries a nutritional cost.
Whenever the intestine encounters stress from pathogens, mycotoxins, heat, poor litter quality, or microbial imbalance, the immune system becomes activated.
The immune response is essential for survival, but it is expensive.
Energy that could support growth is redirected toward immune activity.
Amino acids that could build muscle are utilized to produce immune proteins and inflammatory mediators.
Vitamins and minerals become involved in tissue repair and antioxidant defense.
The bird continues eating, yet a significant proportion of nutrients may no longer be contributing to production.
This phenomenon is often referred to as the “hidden feed cost” of inflammation.

The Silent Performance Thief
One of the greatest misconceptions in poultry production is that intestinal problems always produce visible symptoms.
– Not necessarily.
– Many flocks show normal feed intake, acceptable mortality, and no obvious disease outbreaks. Yet they consistently fail to achieve target performance.
– A slight reduction in nutrient absorption.
– A minor microbial imbalance.
– A low level of intestinal inflammation.
– A subtle increase in intestinal permeability.
Individually these changes may appear insignificant. Collectively they can result in substantial economic losses. This is why gut health is increasingly viewed not as a disease issue but as a performance issue.

The Microbial Workforce Inside Every Bird
Perhaps the most fascinating discovery in recent years is the realization that birds are never truly alone.
The digestive tract contains trillions of microorganisms collectively known as the gut microbiome.
These microbes help digest feed ingredients, produce beneficial metabolites, support intestinal development, influence immune responses, and compete with harmful bacteria.
Some scientists now describe the microbiome as an additional organ because of its profound influence on bird health.
This raises an interesting question:
Are we feeding the bird, or are we feeding its microbiome?
The answer is both.
The future of poultry nutrition may depend as much on managing microbial populations as on balancing nutrients.

Heat Stress: The Gut’s Greatest Enemy
In many poultry-producing regions, heat stress has become one of the most significant challenges affecting gut health.
High environmental temperatures reduce blood flow to the intestine, increase oxidative stress, and compromise intestinal barrier integrity.
As a result, harmful bacterial toxins can cross the intestinal wall and trigger inflammation.
Often the first casualty of heat stress is not growth—it is gut integrity.
This may explain why heat-stressed flocks frequently show poorer FCR, increased wet litter, reduced nutrient utilization, and greater disease susceptibility.
As global temperatures continue to rise, protecting gut health during periods of heat stress will become increasingly important.

The Gut in the Antibiotic-Free Era
The poultry industry is rapidly transitioning toward antibiotic-free and reduced-antibiotic production systems.
While this shift addresses consumer concerns and regulatory requirements, it has also increased attention on intestinal health.
Without routine antibiotic growth promoters, producers must rely on alternative strategies to maintain gut stability.
Probiotics, prebiotics, β-glucans, mannan oligosaccharides (MOS), organic acids, phytogenic compounds, and postbiotics are increasingly being used to support intestinal resilience and microbial balance.
The focus is shifting from killing pathogens to creating an intestinal environment where beneficial microbes and the host can thrive together.

More Birds or More Protein?
The global poultry industry is not being asked to produce more birds.
It is being asked to produce more protein.
As the world’s population grows and consumers increasingly seek affordable animal protein, poultry production continues to expand. Industry projections estimate the sector will grow at a CAGR of approximately 5–7% over the coming years.

But growth alone is not enough.
Producers are expected to deliver more meat with fewer resources, lower feed costs, and a smaller environmental footprint.
This means that every gram of feed matters more than ever before.
And that brings us back to the gut.
Because the difference between feed consumed and protein produced is ultimately determined by the efficiency of the digestive system.

The Future Begins in the Gut
For decades, poultry production focused on genetics, nutrition, and disease control.
The next frontier may be intestinal resilience.
Future improvements in productivity will likely come from better management of inflammation, enhanced barrier integrity, optimized microbiomes, and improved nutrient efficiency within the gastrointestinal tract.
The question may no longer be:

“How much feed did the bird consume?”

Instead, the more important question may be:
“How much of that feed actually became growth?”
The answer lies within the gut.
Not because it is merely another organ, but because it is the organ that determines how effectively all the others perform.
In an era of narrow margins, rising feed costs, heat stress, and antibiotic-free production, the healthiest gut may ultimately become the most valuable asset in the poultry house.

Introduction
Inclusion Body Hepatitis (IBH) is an economically important viral disease of broiler chickens characterized by sudden mortality, hepatitis, and the presence of intranuclear inclusion bodies in liver cells. The disease is primarily caused by Fowl Adenoviruses (FAdVs), particularly serotypes belonging to species D and E. IBH has become increasingly significant worldwide due to its impact on broiler performance, increased mortality, poor feed conversion, and substantial economic losses. The disease mainly affects young broiler chickens between 3 and 7 weeks of age, although birds of other ages may also be affected. Vertical transmission from breeder flocks and horizontal spread through contaminated litter, water, equipment, and personnel play major roles in disease dissemination.

Etiology
IBH is caused by Fowl Adenoviruses (FAdVs), non-enveloped double-stranded DNA viruses belonging to the genus Aviadenovirus within the family Adenoviridae. Several serotypes have been associated with disease outbreaks, including FAdV-2, FAdV-8a, FAdV-8b, and FAdV-11.
Predisposing factors include:
– Immunosuppression caused by Infectious Bursal Disease (IBD)
– Chicken Infectious Anemia (CIA)
– Mycotoxicosis (Poor quality of feed ingredients contaminated with fungus and Mycotoxins).
– Poor Biosecurity and Management
– High stocking density

Clinical Signs
Affected broiler flocks may exhibit:
– Sudden increase in mortality
– Depression and lethargy
– Huddling with Ruffled feathers
– Reduced feed and water consumption
– Usually affects birds of 3 to 5 weeks age, but can be seen in the chicks aging from 4-5 day old.
– Pale comb and wattles
– Poor weight gain
– Diarrhoea with mucoid droppings or green droppings
– Anemia in severe cases
Mortality rates generally range from 5–15%, but outbreaks may occasionally result in mortality exceeding 30%.

Post-Mortem Lesions
The most characteristic lesions are observed in the liver.
Gross Lesions
Liver
– Enlarged, swollen, and pale liver
– Yellowish discoloration
– Multifocal necrotic foci
– Petechial and ecchymotic hemorrhages
– Friable consistency
Kidneys
– Enlarged and pale kidneys
– Congestion
Heart
– Hydropericardium may occasionally be present
– Pale myocardium
Spleen
– Enlargement and congestion
Histopathological Lesions
Microscopic examination reveals:
– Severe hepatic necrosis
– Basophilic intranuclear inclusion bodies in hepatocytes
– Degeneration and destruction of liver cells
– Mononuclear cell infiltration
The presence of characteristic intranuclear inclusion bodies is considered pathognomonic for IBH.

Serology
Serological testing is useful for monitoring flock exposure and breeder immunity.
Common serological methods include:
ELISA (Enzyme-Linked Immunosorbent Assay)
– Detects antibodies against Fowl Adenovirus
– Useful for flock monitoring
– Evaluates maternal antibody levels
Virus Neutralization Test (VNT)
– Determines serotype-specific antibodies
– Primarily used in research and epidemiological investigations
Interpretation
– High antibody titers in breeders provide maternal protection to progeny.
– Seroconversion in broilers indicates field exposure.
– Paired serum samples can help determine recent infection.
Diagnosis
Diagnosis should be based on a combination of clinical history, post-mortem findings, histopathology, and laboratory confirmation.
Field Diagnosis
Suspect IBH when:
– Sudden mortality occurs in 3–7 week-old broilers.
– Enlarged, pale, hemorrhagic liver is observed.
– There is a history of immunosuppressive diseases.
Laboratory Diagnosis
Histopathology
– Demonstration of intranuclear inclusion bodies in hepatocytes.
Polymerase Chain Reaction (PCR)
– Highly sensitive and specific.
– Detects and identifies FAdV serotypes.
Virus Isolation
– Performed in chicken embryo liver cells or embryonated eggs.
Immunohistochemistry
– Detects adenoviral antigen within tissues.
Sequencing
– Used for epidemiological studies and strain characterization.

Treatment
There is no specific antiviral treatment for Inclusion Body Hepatitis.

Management is mainly supportive:
Supportive Therapy
– Multivitamin supplementation
– Vitamin E and Selenium administration
– Use D’Bio-Mix 20-25 mL per 100 birds and ABES-URZZA 20 ml for 100 birds.
– Ionic electrolyte (ABESTRAL) supplementation and probiotic prebiotic supplementation
— Adequate hydration
Control of Secondary Infections
– Antibiotics may be administered under veterinary supervision to control secondary bacterial infections.
Management Measures
– Reduce stress factors
– Improve ventilation
– Maintain litter quality
– Ensure proper nutrition

Prevention and Control
Effective prevention relies on biosecurity and breeder vaccination.

Biosecurity Measures
– All-in/all-out management
– Thorough cleaning and disinfection
– Restriction of farm visitors
– Proper disposal of dead birds
– Control of rodents and insects
– Sanitation of equipment and vehicles
Breeder Flock Management
– Monitor antibody levels regularly.
– Vaccinate breeders to ensure maternal antibody transfer.
– Prevent immunosuppressive diseases such as IBD and CIA.
Control of Vertical Transmission
– Maintain healthy breeder flocks.
– Conduct routine serological surveillance.
– Implement strict hatchery hygiene.

Vaccination Schedule
Vaccination strategies vary according to local epidemiology and circulating serotypes.
Breeder Vaccination Program
Age Vaccine
8–10 weeks Killed IBH (primary dose)
14–16 weeks Booster dose
18–20 weeks (before lay) Optional booster in high-risk areas
Broiler Vaccination
Routine vaccination of broilers is generally not practiced in many regions because protection is primarily achieved through maternal antibodies. However, live or inactivated vaccines may be considered in endemic areas under veterinary guidance.
Objectives of Vaccination
– Prevent vertical transmission
– Enhance maternal antibody levels
– Reduce mortality and production losses
– Improve flock uniformity

Economic Impact
IBH can result in:
– Increased mortality
– Poor growth performance
– Reduced feed efficiency
– Higher medication costs
– Increased carcass condemnation
– Significant financial losses to poultry producers

Conclusion
Inclusion Body Hepatitis remains an important viral disease of modern broiler production. Early diagnosis, strict biosecurity, breeder vaccination, and effective management practices are essential for disease prevention and control. Maintaining strong maternal immunity through breeder vaccination and minimizing immunosuppressive conditions can significantly reduce the impact of IBH on commercial poultry operations.

Introduction
The poultry industry is one of the fastest-growing segments of global agriculture and plays a crucial role in ensuring food security, nutritional sustainability, and rural livelihoods. Poultry meat and eggs are among the most affordable and widely consumed sources of high-quality animal protein. However, the economic sustainability of poultry farming is increasingly threatened by rising feed costs, which account for nearly 65–75% of total production expenditure in commercial poultry enterprises. Among feed ingredients, soybean meal (SBM) constitutes the primary protein source because of its superior amino acid profile, high digestibility, and consistent nutrient availability. Nevertheless, volatility in soybean prices due to climate change, global trade disruptions, geopolitical conflicts, biofuel competition, transportation costs, and fluctuating international commodity markets has significantly increased production costs in poultry farming. The dependence on imported soybean meal in many developing countries, including India, further exposes poultry producers to supply chain uncertainties and foreign exchange fluctuations. Consequently, poultry nutritionists and farm managers are actively exploring alternative protein sources and innovative farm management strategies to reduce feed costs while maintaining productivity, flock health, and profitability. Simultaneously, advances in precision poultry farming, digital technologies, environmental control systems, and feed efficiency optimization are transforming poultry production into a more data-driven and economically resilient enterprise. The integration of nutritionally viable soymeal alternatives with smart farm management practices offers a promising pathway toward sustainable poultry production under conditions of escalating feed prices.

Importance of Soybean Meal in Poultry Nutrition
Soybean meal has long been regarded as the benchmark protein ingredient in poultry diets because of its excellent nutritional characteristics. Typically containing 44–48% crude protein, soybean meal provides an ideal balance of essential amino acids, particularly lysine, which is often limiting in cereal-based diets. Its high digestibility, palatability, and relatively low fibre content make it highly suitable for broilers, layers, breeders, and turkeys.
In broiler nutrition, soybean meal supports rapid muscle development, efficient feed conversion, and improved carcass quality. In layer production, it contributes to enhanced egg production, egg mass, and shell quality. Furthermore, soybean meal contains beneficial bioactive compounds and functional peptides that positively influence gut health and immune responses.

Despite these advantages, excessive dependence on soybean meal has created several challenges for the poultry industry. Global soybean production is concentrated in a limited number of countries, making supply chains vulnerable to climatic events, geopolitical instability, and export restrictions. Additionally, soybean cultivation has been associated with deforestation, biodiversity loss, and environmental concerns, especially in South America. Increasing competition between feed, food, and biofuel sectors has also intensified pressure on soybean availability and pricing.

As feed costs continue to rise, the poultry industry is increasingly compelled to diversify protein sources and adopt more economically sustainable feeding strategies.

Economic Consequences of Rising Feed Cost in Poultry Production
Feed cost inflation directly reduces profit margins in poultry enterprises. Since poultry production operates on relatively narrow economic margins, even modest increases in feed prices can significantly affect profitability. Broiler production is particularly sensitive because of short production cycles and high feed consumption rates. Similarly, in layer operations, prolonged periods of elevated feed prices may substantially reduce returns over feed cost.

Rising feed costs result in several economic consequences:
– Increased cost per kilogram of live weight gain.
– Reduced feed conversion efficiency under poor-quality diets.
– Decline in egg production profitability.
– Increased market price of poultry products.
– Reduced competitiveness of small-scale producers.
– Lower farm expansion and investment capacity.

In many regions, feed manufacturers and poultry producers respond by reformulating diets with lower-cost ingredients. However, indiscriminate replacement of soybean meal without proper nutritional balancing may impair growth performance, immunity, carcass quality, and reproductive efficiency. Therefore, economically sustainable poultry production requires a scientific approach that combines alternative feed ingredients with precision nutritional management.

Oilseed Meals as Alternatives to Soybean Meal
Oilseed by-products are among the most practical alternatives to soybean meal in poultry feeding systems. Several oilseed meals possess substantial protein content and can partially replace soybean meal when diets are appropriately formulated.

Canola Meal
Canola meal contains approximately 35–40% crude protein and is rich in sulphur-containing amino acids. It can effectively replace part of soybean meal in broiler and layer diets. However, its higher fibre content and presence of glucosinolates may limit inclusion levels.

Sunflower Meal
Sunflower meal is another important protein source with good methionine content. Dehulled sunflower meal possesses improved nutrient density and can be used efficiently in poultry rations. Enzyme supplementation enhances its digestibility.

Cottonseed Meal
Cottonseed meal provides substantial protein but contains gossypol, a toxic pigment that restricts its inclusion in poultry diets. Proper processing and iron supplementation may reduce toxicity concerns.

Groundnut Cake
Groundnut cake is widely used in India and other Asian countries because of its local availability and moderate protein content. However, aflatoxin contamination remains a major concern requiring strict quality control measures.

Sesame and Linseed Cakes
These oilseed cakes provide supplementary protein and beneficial fatty acids, although their use is often limited by fibre content and anti-nutritional factors. Oilseed meals can substantially reduce feed costs when incorporated scientifically with amino acid balancing and enzyme supplementation.

Use of Legume Grains in Poultry Feeding
Legume grains are gaining popularity as sustainable and locally available protein alternatives in poultry nutrition. Commonly used legumes include peas, lupins, chickpeas, pigeon pea, and faba beans.
Nutritional Advantages
– Moderate to high protein content.
– Good starch availability.
– Reduced dependence on imported soybean meal.
– Nitrogen fixation benefits in agriculture.
– Lower environmental footprint.

Constraints
– Presence of tannins, trypsin inhibitors, lectins, and non-starch polysaccharides.
– Lower methionine content compared to soybean meal.
– Variability in nutrient composition.

Modern processing technologies such as extrusion, roasting, soaking, dehulling, and fermentation help reduce anti-nutritional factors and improve nutrient utilization. In broiler diets, partial replacement of soybean meal with processed legumes has demonstrated satisfactory growth performance and feed efficiency.
The use of locally cultivated legumes can also strengthen regional feed security and reduce transportation-related costs.

Distillers Dried Grains and Agro-Industrial By-Products
Agro-industrial by-products represent an economically valuable resource for poultry feeding. The poultry industry increasingly utilizes these ingredients within circular economy models aimed at reducing waste and improving resource efficiency.

Distillers Dried Grains with Solubles (DDGS)
DDGS is a by-product of ethanol production and contains considerable protein, fat, phosphorus, and digestible energy. It is widely used in broiler and layer diets at moderate inclusion levels.
Rice Bran
Rice bran is abundantly available in rice-producing countries and provides energy, oil, vitamins, and moderate protein. Stabilization is necessary to prevent rancidity.
Wheat Bran and Pollard
These by-products supply fibre, phosphorus, and moderate protein but are generally used at lower inclusion rates in poultry because of high fibre levels.
Brewer’s Grains
Brewer’s grains can serve as low-cost feed ingredients after proper drying and preservation.
Bakery Waste
Processed bakery waste offers a highly digestible energy source capable of partially replacing maize in poultry diets. Although agro-industrial by-products reduce feed costs, variability in nutrient composition necessitates routine laboratory analysis and quality assurance.

Insect Meal as a Novel Protein Source
Insect meal has emerged as a highly promising alternative protein source for poultry production. Black soldier fly larvae meal, mealworm meal, and housefly larvae meal possess high crude protein levels and favourable amino acid profiles.

Advantages of Insect Meal
– Excellent digestibility.
– High protein concentration.
– Efficient conversion of organic waste into biomass.
– Reduced land and water use.
– Lower environmental impact compared to soybean cultivation.

Studies have shown that insect meal can partially replace soybean meal and fishmeal in broiler diets without adversely affecting growth performance or carcass quality. Some insect-derived lipids also possess antimicrobial properties that may support gut health.

However, large-scale commercialization faces several limitations:
– High production costs.
– Regulatory constraints.
– Limited industrial infrastructure.
– Consumer perception challenges.
As production technologies improve, insect meal may become increasingly competitive as a sustainable protein source for poultry feeding.

Algae, Single Cell Proteins, and Fermented Feed Ingredients
Microalgae and microbial proteins represent future-oriented feed resources with substantial potential for poultry nutrition.

Microalgae
Species such as Spirulina and Chlorella contain high-quality protein, essential fatty acids, vitamins, minerals, and pigments. In layer diets, algae supplementation enhances yolk pigmentation and antioxidant status.
Single Cell Protein (SCP)
Yeast, bacteria, and fungal biomass can provide highly digestible protein with rapid production rates and minimal land requirement.
Fermented Feed Ingredients
Fermentation improves nutrient availability and reduces anti-nutritional compounds in feed ingredients. Fermented soybean meal, fermented legumes, and probiotic-enriched feeds enhance gut health and nutrient absorption in poultry.

These technologies contribute to improved feed conversion efficiency and may reduce dependence on expensive conventional protein sources.

Precision Nutrition and Least-Cost Feed Formulation
Precision nutrition is essential for maintaining profitability during periods of feed cost escalation. Modern least-cost formulation software allows nutritionists to design diets that meet nutrient requirements at minimum cost while incorporating alternative ingredients.

Major Precision Nutrition Approaches
– Digestible amino acid formulation.
– Ideal protein concept.
– Phase feeding.
– Precision protein nutrition.
– Net energy systems.
– Use of synthetic amino acids.

The supplementation of lysine, methionine, threonine, valine, and tryptophan enables significant reduction in crude protein levels without compromising performance. Lower protein diets reduce feed cost, nitrogen excretion, and metabolic stress.

Feed enzymes such as phytase, xylanase, protease, and β-glucanase further enhance nutrient digestibility and improve utilization of unconventional feed ingredients.

Precision nutrition therefore represents a cornerstone strategy for economical poultry production under volatile feed markets.

Smart Feeding Systems and Feed Wastage Reduction
Feed wastage significantly contributes to economic losses in poultry farming. Smart feeding technologies help optimize feed distribution, minimize wastage, and improve feed efficiency.

Important Smart Feeding Technologies
– Automated feeding systems.
– Sensor-based feed dispensers.
– Precision feed allocation systems.
– Real-time feed intake monitoring.
– Smart silos and inventory systems.
Automated systems ensure uniform feed distribution and reduce labour dependency. Sensor technologies can detect abnormal feed consumption patterns, enabling early identification of health or management problems.

Proper feeder design, adjustment of feeder height, and prevention of feed spillage also play important roles in minimizing wastage. Even small reductions in feed wastage can substantially improve farm profitability during periods of high feed prices.

Environmental Control and Poultry House Management
Environmental management strongly influences feed intake, nutrient utilization, and overall poultry performance. Poor environmental conditions reduce growth rate, impair immunity, and worsen feed conversion efficiency.

Critical Environmental Factors
– Temperature.
– Humidity.
– Ventilation.
– Air quality.
– Lighting programs.
– Litter management.

Heat stress is particularly detrimental in tropical and subtropical poultry production systems. Birds exposed to high temperatures reduce feed intake, resulting in lower body weight gain and egg production.

Modern environmentally controlled poultry houses utilize:
– Tunnel ventilation.
– Evaporative cooling systems.
– Automated climate control.
– Smart sensors for temperature and humidity monitoring.
These systems help maintain optimal environmental conditions, improve bird comfort, and enhance feed efficiency.

Gut Health Management and Feed Efficiency
Maintaining optimal gut health is essential for efficient nutrient utilization and profitability in poultry production. Intestinal health directly affects digestion, absorption, immunity, and feed conversion efficiency.

Key Gut Health Strategies
– Probiotics.
– Prebiotics.
– Organic acids.
– Phytogenic feed additives.
– Enzymes.
– Competitive exclusion products.

The reduction in antibiotic growth promoter usage has increased the importance of alternative gut health management approaches. Healthy intestinal microflora improves nutrient digestibility and reduces disease susceptibility.

Mycotoxin management is equally critical because contaminated feed ingredients can impair gut integrity, suppress immunity, and reduce productivity. The use of toxin binders and strict feed quality control helps maintain flock performance under challenging feeding conditions.

Digital Technologies and Precision Poultry Farming
Precision poultry farming integrates digital technologies, automation, sensors, artificial intelligence, and data analytics to optimize poultry production efficiency.

Applications of Precision Poultry Farming
– Real-time flock monitoring.
– Automated mortality detection.
– Feed and water consumption analysis.
– Environmental monitoring.
– Predictive disease surveillance.
– Behavioural analysis using cameras and sensors.

Artificial intelligence-based systems can identify deviations in flock behaviour before visible clinical signs appear. Early disease detection reduces mortality losses and treatment costs.

Cloud-based management platforms allow integration of production, nutrition, health, and financial data for better decision-making. Data-driven management improves resource utilization and supports economic sustainability.

Sustainability and Climate-Resilient Poultry Production

Sustainable poultry production requires balancing economic profitability with environmental responsibility. Rising feed costs and climate-related disruptions highlight the need for resilient feeding systems and efficient resource utilization.

Important Sustainability Strategies
– Diversification of feed ingredients.
– Use of locally available feed resources.
– Circular economy approaches.
– Reduction of feed carbon footprint.
– Water conservation.
– Renewable energy utilization.

Climate-smart poultry production systems emphasize resilience against heat stress, feed shortages, disease outbreaks, and market volatility. Alternative proteins such as legumes, insect meal, algae, and agro-industrial by-products contribute to greater feed system sustainability.

The integration of smart technologies further improves resource efficiency and environmental performance.

Way Forward
Rising feed costs represent one of the most significant challenges confronting modern poultry production systems. Since soybean meal remains a major contributor to feed expenses, reducing dependency on conventional soybean-based diets has become an economic necessity for poultry producers worldwide. A wide range of alternative protein sources—including oilseed meals, legumes, agro-industrial by-products, insect meal, algae, microbial proteins, and fermented feed ingredients—offer considerable potential for reducing feed costs while maintaining productive performance.

However, successful incorporation of soymeal alternatives requires scientific feed formulation, proper ingredient processing, amino acid balancing, quality control, and strategic use of feed additives and enzymes. No single alternative ingredient can completely replace soybean meal under all production conditions; therefore, diversified and flexible feeding programs are essential.

Equally important is the adoption of smart farm management systems that improve feed efficiency and operational sustainability. Precision nutrition, automated feeding systems, environmental control technologies, gut health management, digital monitoring platforms, and artificial intelligence-based decision support systems can substantially enhance profitability during periods of volatile feed prices.

The future poultry industry will increasingly depend on the integration of alternative feed resources with precision poultry farming technologies. Producers capable of combining nutritional innovation, smart management, and sustainability-oriented practices will be better positioned to withstand economic uncertainties and maintain long-term profitability. Thus, exploring soymeal alternatives alongside intelligent farm management is not merely a temporary response to rising feed costs, but a strategic transformation toward resilient, efficient, and sustainable poultry production systems for the future.

The 5th Edition of the Global Talks series presents an in-depth conversation with Dr. Nasir Mukhtar, a globally recognized leader and influential voice shaping the poultry industry across the GCC and Asian regions. The discussion explores the rapidly evolving landscape of poultry science, industry leadership, and knowledge-driven innovation that is redefining the future of global poultry production. With decades of experience spanning academia, industry, and international poultry organizations, Dr. Mukhtar has played a transformative role in advancing poultry science while strengthening industry–academia collaboration. Currently serving as the General Secretary of the World’s Poultry Science Association (WPSA), UAE Branch, he actively champions the integration of scientific research with practical industry solutions, the development of young professionals, and the resolution of emerging challenges through global cooperation and informed leadership.

Dr. Mukhtar began his research career in the breeding of native chickens, successfully combining scientific rigor with real-world industry applications.

While reflecting on his research journey during the discussion, Dr. Mukhtar shared his dual role as a Professor and poultry entrepreneur, enabled him pioneered groundbreaking research on standardized ileal digestible (SID) amino acid values in sex-based broilers, establishing a globally relevant model for precision poultry nutrition.

He has led and completed several landmark collaborative projects with prestigious international institutions and organizations. Responding during the interaction, Dr. Mukhtar recalled earning his Ph.D. from the University of Agriculture, Faisalabad, Pakistan, and completed his post-doctoral research at the Roslin Institute, University of Edinburgh, Scotland (UK).

Throughout his academic career, Dr. Mukhtar has supervised ten Ph.D. and twenty M.Phil. students, making a lasting contribution to human capacity development in the poultry sector. He is the author of six books and sixty-three peer-reviewed national and international research articles, widely cited across scientific and industry platforms.
Beyond research, Dr. Mukhtar’s global leadership extends to key strategic roles. During the interaction Dr. Mukhtar detailed his responsibilities as General Secretary of the WPSA UAE Branch, Vice President of the Asian Pacific Federation of WPSA (Thailand), and Global Chair of the WPSA Working Group on Small-Scale Family Poultry Farming.
He is also a member of the Editorial Board of the World’s Poultry Science Journal and serves as a Guest Editor for Poultry Science.

A frequent and respected speaker at international scientific and industry forums, Dr. Nasir Mukhtar continues to influence global poultry policy, innovation, and sustainability—bridging science with industry and shaping the next generation of poultry leaders.

In the third edition of Global Talks, I engaged in an insightful discussion with Mr. Ahmad Omar, Regional Strategic Account Manager at Boehringer Ingelheim Animal Health, based in Dubai. The interaction explored the rapidly evolving dynamics of poultry health management across emerging markets and the increasing shift toward prevention-led, science-driven strategies that support sustainable, efficient, and responsible poultry production. Mr. Omar shared perspectives on Boehringer Ingelheim’s strong global commitment to animal health and welfare, outlining how innovative vaccine solutions, advanced vaccination technologies, and deep veterinary expertise are empowering poultry producers throughout the IMETA region (India, Middle East, Turkey, and Africa) to manage disease risks and enhance overall flock performance. He also highlighted India’s fast-growing poultry sector, pointing to significant opportunities for integrated health solutions, strengthened biosecurity frameworks, and collaborative partnerships to drive long-term, sustainable industry growth.

The Role of Prevention in Animal Health
Mr. Ahmad Omar highlighted that Boehringer Ingelheim firmly believes in “Prevention Works”, reflecting a strategic shift from treatment-focused approaches to preventive healthcare solutions. He explained that proactive vaccination, robust biosecurity, and science-based management practices are essential to ensure safe, sustainable, and efficient poultry production, particularly in fast-growing markets such as IMETA.

He also noted that animal health is closely linked to food security, public health, and economic development, making prevention-led strategies critical for governments, veterinarians, and producers alike. Dr. Omar further emphasized that early disease prevention not only reduces mortality and production losses but also helps improve predictability, consistency, and profitability at the farm level.

IMETA: A Strategic Growth Region
Discussing the IMETA region, Mr. Omar outlined why it is strategically important for Boehringer Ingelheim Animal Health:
Key Portfolio Focus
– Poultry vaccines and vaccination technologies
– Parasiticides and preventive solutions for companion animals
– Ruminant health and productivity solutions
Market Drivers
– Expanding commercial poultry production
– Rising biosecurity and disease challenges
– Growing awareness of pet health and preventive care
Strategic Priorities
– Excellence in launching innovative vaccines
– Strengthening partnerships with distributors, veterinarians, and industry stakeholders
– Leveraging digital tools for disease monitoring and farmer engagement

India: A Key Driver of Regional Growth
Speaking about India, Mr. Ahmad Omar described the country as one of the fastest-growing poultry markets globally. He noted that the sector’s growth is driven by rising protein demand, increased focus on biosecurity, and strong interest in preventive health measures.

Mr. Omar highlighted Boehringer Ingelheim’s leadership in poultry health through vaccines such as Vaxxitek® and Prevexxion®, which help control major diseases like Infectious Bursal Disease (IBD) and Marek’s Disease, thereby enhancing flock performance and improving food safety. He also emphasized the rapid expansion of India’s companion animal segment, with increasing pet ownership driving demand for parasiticides and preventive healthcare solutions, supported by strategic collaborations with local distributors.

Innovation, Partnerships, and Knowledge Sharing
Mr. Omar stressed that collaboration is central to Boehringer Ingelheim’s regional strategy:
– Veterinary and Academic Engagement: Partnering with veterinary associations and academic institutions to promote best practices in poultry and pet care.
– Digital Transformation: Deploying tools for disease tracking, planning, and data-driven decision-making for veterinarians and farmers.
– Training and Education: Conducting technical seminars, workshops, and programs to enhance preventive healthcare knowledge and improve on-farm implementation.

Sustainability and Community Impact
Mr. Omar highlighted Boehringer Ingelheim’s commitment to sustainability and responsible practices:
– Rabies Elimination: Supporting the global “Zero by 30” initiative to eradicate dog-mediated rabies through vaccination campaigns and awareness programs.
Reducing Antibiotic Dependence: Encouraging preventive vaccination and biosecurity measures to minimize antibiotic usage in livestock.
Capacity Building: Training veterinarians and farmers on responsible farming practices and animal welfare.
Community Development: Enhancing access to veterinary care in rural and underserved areas.
Environmental Responsibility: Reducing operational carbon footprint and promoting eco-friendly packaging.

Future Outlook
Concluding the discussion, Mr. Ahmad Omar shared Boehringer Ingelheim’s forward-looking vision for IMETA and India:
– Leadership in next-generation poultry vaccines for Avian Influenza, IBD, and Newcastle Disease
– Expansion into emerging segments such as aquaculture and advanced diagnostics
– Continued investment in digital innovation, sustainability, and prevention-focused programs

He reaffirmed the company’s commitment to supporting India’s poultry sector through science-driven solutions, strategic partnerships, and long-term sustainable growth initiatives.

The landmark conference, organized by the World Poultry Science Association (WPSA) UAE, brought together over 200 global industry leaders, researchers, and policymakers to address pressing food security challenges.

Among the technology innovators presenting breakthrough solutions, to share knowledge and explore the future of sustainable poultry production. Beyond the science and data, what truly drives progress in our field is the power of networking, shared learning and meaning full collaboration.

The Eminent speakers at this conference included Dr. Nasir Mukhtar, Conference Secretary, Dr. Peter van Horne, Secretary General, WPSA (Netherlands), Mr. Kevin Roepke. Executive Director, MENASA-USSEC, Dr. M. Reza Abdullahi, Professor of Poultry Nutrition, Massey University, New Zealand, Mr. Russel Sadati, La Meccinica, Italy, Dr. Jean Paul Ruckebusch, France, Dr. Miriam Alberto Tempra, Australia, Mr. Nan-Dirk Mulder, USA, Mr. Jorg Hurlin, Germany, Dr. Mathew Clark, MD, Feed Guys Resources Pte Ltd., Malaysia, Ms. Christelle Cordahi, Regional Head, Sustainability & Human Utilization, USSEC-MENSA, Mr. Ricky Thaper, India, Mr. Shakeel Ahmed, Co-Founder and COO, Poulta Inc., USA and a few others.

I had the privilege to deliver a presentation on “Driving Sustainable Growth of Indian Poultry Industry through Artificial Intelligence (AI) Tools”, highlighting how India’s poultry sector is adopting smart and data-driven technologies to ensure productivity, efficiency, and sustainability.

The conference offered an excellent opportunity to exchange ideas, learn global best practices, and strengthen collaborations across regions. This conference was sponsored by Al Ain Farms-UAE, Poulta Inc.-USA, Innovad Group and La Meccanica-Italy.

There were also two difference sessions on Ventilation workshop and Breeder & Hatchery Manager workshop. Congratulations to Dr. Nasir Mukhtar, Conference Secretary and WPSA-UAE Team for this valuable platform and all fellow speakers, partners and delegates for the enriching discussions as it’s always inspiring to contact with passionate professionals and industry experts from around the world.