The meeting commenced with an introductory address by Mr. Deepak Khosla, General Manager (Marketing), who welcomed the participants and highlighted the company’s commitment to delivering science-based solutions for the poultry industry.

Dr. Prakash Reddy, DGM (Technical), delivered a currently relevant and focused presentation on “Hatchery Vaccines and Vaccination: Catching the Future”. He emphasized on the emergence of pathogens which are critical for designing effective control strategies because it reveals key vulnerabilities, transmission dynamics (vertical), and potential immune evasion mechanisms. Highlighted the emerging vaccine technologies opening new fields of possibilities for disease control and disease management, which include genotype based vaccines, vector vaccines, immune complex vaccine etc. The novel vaccine technologies would likely impose completely novel immune pressure or selection for resistance with enhanced immunosuppression and changes in patterns of antigenic variation, tissue tropism, and invasion pathways, so should be selective. Lastly, he updated the Innovative hatchery vaccination methods adapted in India for mass administration with speed and accuracy with ease of adaptation of semi-automated subcutaneous vaccination, spray vaccination etc. in day old chicks with a check on vaccinal reactions, errors and miss outs.

The second session, “Improving Broiler Performance through Effective Water Sanitation and Precise Medication Dosing,” was presented by Dr. Datta Kulkarni, DGM (Technical). He discussed how good water quality, effective sanitation, and accurate medication dosing can help enhance broiler health, performance, and farm profitability.

The programme concluded with valuable remarks from Mr. H. S. Padda, DGM, (Marketing), who underlined the importance of adopting scientific and practical approaches to address emerging poultry health challenges. Mr. Shashi Bhushan, AGM, (Marketing), delivered the vote of thanks and expressed gratitude to the speakers and participants for making the meeting informative and successful.

The technical meeting reaffirmed Ventri Biologicals’ commitment to advancing poultry health through knowledge sharing, innovation, and effective field-level solutions.

Introduction : Every year, invisible contaminants hidden within grains and feed ingredients silently reduce livestock productivity. Mycotoxins—naturally occurring toxic compounds produced by fungi—are responsible for millions of dollars in economic losses through poor growth, reduced immunity, reproductive disorders, lower feed efficiency, and increased mortality. Although impossible to see with the naked eye, their impact on poultry, swine, and dairy production is enormous.

What Are Mycotoxins?
Mycotoxins are toxic secondary metabolites produced by moulds such as Aspergillus, Fusarium, and Penicillium. Scientists have identified over 300 different mycotoxins, and studies indicate that nearly one-quarter of global feed supplies may be contaminated.
The most economically important toxins include:
-Aflatoxins
– Ochratoxins
– Fumonisins
– Deoxynivalenol (DON)
– T-2 Toxin
– Zearalenone
Each affects animals differently, but all reduce productivity and profitability.

Why Do Mycotoxins Develop?
Moulds flourish when four conditions come together:
– Warm temperatures
– High humidity
– Moisture in grains
– Oxygen
Once established, fungal growth continues during harvesting, storage, transportation, and feed manufacturing unless properly controlled.

India’s Mycotoxin Challenge
Recent testing presented in the report paints a worrying picture. 6,304 feed analysis, 99% contamination, and 83% above the performance-risk threshold.
Key Findings

– 6,304 feed analysis conducted
– 99% showed detectable contamination
– 83% exceeded performance-risk thresholds
Among ingredients, DORB, peanut meal, maize, soybean meal, DDGS, and corn gluten all showed significant contamination levels.

Multiple Mycotoxins: A Greater Threat
Animals are rarely exposed to a single toxin.
Instead, feeds commonly contain multiple mycotoxins that interact synergistically, making the combined damage significantly greater than the effect of individual toxins. This explains why even relatively low toxin concentrations can cause substantial production losses.

Economic Impact on Farms
The consequences are visible across every production system.

Poultry
– Lower feed intake
– Reduced weight gain
– Poor feed conversion
– Thin eggshells
– Lower hatchability
– Fatty liver
– Weak immunity

Swine
– Reproductive disorders
– Embryonic mortality
– Vomiting
– Reduced growth
– Feed refusal
– Tail necrosis
– Liver and kidney damage
Ultimately, these problems translate directly into economic losses through poorer animal performance.

The Hidden Cost: Immune Suppression
– One of the most damaging effects of mycotoxins is their ability to suppress the immune system.
– Animals become more vulnerable to bacterial and viral infections while showing reduced responses to vaccines and treatments.
– This means disease outbreaks become more severe and recovery becomes slower.

Can Nutrition Help?
Nutritional interventions can reduce the impact of toxins.

Recommended approaches include:
– Higher amino acid supplementation
– Vitamins E, C, and D3
– Selenium
– Choline chloride
– Liver-support products
– Mold inhibitors
– Broad-spectrum toxin binders
These measures improve resilience while reducing toxin damage.

Scientific Toxin Elimination Management (STEM-500)
An effective strategy combines four complementary actions:
1. Prevention
Prevent fungal growth before toxins develop.
2. Elimination
Bind multiple mycotoxins irreversibly.
3. Neutralization
Use enzymatic systems to neutralize toxins.
4. Gut Ecology Enhancement
Improve gut health while strengthening immunity and reducing pathogen pressure. This integrated approach offers broader protection than relying on toxin binders alone.

Featured Solution: STEM-500
The presentation introduces STEM-500, a multi-component toxin management product formulated with:
– Specially treated HSCAS
– Organic acids
– Oxine Copper
– MOS
– Bio-active phytocompounds
– Polyphenols
– Lactobacillus
– Lipotropic agents
According to the presentation, the product is designed to reduce mould growth, bind multiple mycotoxins, minimize endotoxin effects, improve liver function, support gut health, and enhance feed conversion, growth, and survival.

Conclusion
Mycotoxins remain one of the most significant hidden threats in modern animal production. Since contamination can occur throughout the grain supply chain, prevention alone is rarely sufficient. A comprehensive management strategy—combining mould control, toxin binding, detoxification, and gut health support—is essential for maintaining animal health and maximizing production efficiency.

Biosecurity as an Investment: Why Disease Prevention delivers the Best Return on Investment (ROI) in Poultry Production

Prof. (Dr.) P.K. Shukla and Dr. Amitav Bhattacharyya
Department of Poultry Science, College of Veterinary Science and
Animal Husbandry, Mathura- 281001 (U.P.)

Introduction
Over the last five decades, the poultry industry has undergone a remarkable transformation. Scientific advances in genetics, nutrition, housing, disease control, and management have enabled producers to achieve unprecedented levels of productivity. Poultry meat and eggs have become among the most affordable and nutritious sources of animal protein, making the industry indispensable for global food and nutritional security. In India, poultry production has developed into an important agribusiness sector, generating employment for millions of people while supporting allied industries such as hatcheries, feed manufacturing, pharmaceuticals, processing, transportation, and retail.

Despite these achievements, infectious diseases remain one of the greatest constraints to sustainable poultry production. Diseases such as avian influenza, Newcastle disease, infectious bronchitis, infectious bursal disease, Marek’s disease, coccidiosis, salmonellosis, and mycoplasmosis continue to cause substantial economic losses. These diseases not only reduce flock productivity but also affect food safety, consumer confidence, international trade, and public health.

Under modern intensive production systems, disease outbreaks spread rapidly because of high stocking densities, frequent movement of birds and equipment, and increasing interactions among farms. Once pathogens establish themselves within a flock, economic losses accumulate through mortality, reduced growth, poor feed conversion, lower egg production, treatment expenses, and market disruptions. Consequently, preventing disease introduction is far more economical than managing disease after it has occurred.

Biosecurity has therefore become the foundation of modern poultry health management. It is no longer viewed merely as a collection of hygiene practices but as a comprehensive risk management strategy designed to prevent disease while maximizing productivity and profitability.

Economic Impact of Poultry Diseases
The financial consequences of poultry diseases extend far beyond mortality alone. Disease outbreaks affect every component of the production chain, from breeder farms and hatcheries to processing plants, retailers, and consumers.

Direct economic losses include increased mortality, poor weight gain, reduced egg production, inferior feed conversion efficiency, decreased hatchability, veterinary expenses, medication costs, diagnostic testing, and emergency vaccination programmes. Even mild infections that do not cause obvious mortality often reduce flock performance sufficiently to eliminate expected profit margins.

Indirect losses are frequently even greater. Disease outbreaks can result in movement restrictions, export bans, lower consumer demand, reduced processing efficiency, insurance costs, and disruption of supply chains. Highly pathogenic avian influenza has repeatedly demonstrated how a single outbreak can result in massive financial losses through depopulation, compensation payments, and trade restrictions.
Equally damaging are the hidden costs associated with subclinical infections. Chronic disease reduces flock uniformity, suppresses immune responses, increases susceptibility to secondary infections, and diminishes reproductive performance without producing dramatic clinical signs. Such losses often remain unnoticed but continuously erode farm profitability.
These economic realities highlight an important principle: disease prevention should not be regarded solely as a veterinary responsibility but as an essential business strategy that protects investments in chicks, feed, labour, housing, equipment, and marketing.

Prevention Versus Treatment: The Economics of Biosecurity
The principle that “prevention is better than cure” has special relevance in commercial poultry production. Intensive poultry systems house thousands of genetically similar birds in close proximity, allowing infectious agents to spread extremely rapidly once introduced.

By the time clinical signs become evident, pathogens have often multiplied extensively within the flock and contaminated the surrounding environment. Even if treatment successfully controls mortality, birds rarely regain their original production potential. Reduced feed efficiency, slower growth, delayed marketing age, poor egg production, and increased susceptibility to secondary infections frequently persist throughout the production cycle.
Treatment also involves considerable expenditure on antibiotics, supportive medications, laboratory investigations, veterinary consultation, and labour. These costs are incurred after production losses have already begun, thereby reducing overall profitability.
Biosecurity interrupts pathogen transmission before infection becomes established. Investments in perimeter fencing, controlled farm access, sanitation, water treatment, pest management, employee training, and visitor control substantially reduce the probability of disease introduction. Unlike treatment costs, preventive investments continue generating economic returns throughout successive production cycles by maintaining flock health and preserving production efficiency.
Numerous studies have shown that the cost of implementing effective biosecurity programmes is significantly lower than the cumulative losses associated with disease outbreaks. Consequently, biosecurity functions as a form of biological insurance that safeguards every other investment made in poultry production.

Principles of Poultry Biosecurity
Biosecurity is a science-based management system aimed at preventing the introduction, establishment, and spread of infectious agents. Effective biosecurity requires an integrated approach involving infrastructure, operational procedures, personnel behaviour, environmental sanitation, and continuous monitoring.
Three fundamental principles form the basis of poultry biosecurity:

Bio-exclusion focuses on preventing pathogens from entering the farm through controlled access, procurement of healthy chicks, vehicle disinfection, quarantine, and visitor management.

Bio-containment prevents infectious agents from spreading outside infected premises by implementing movement restrictions, proper disposal of carcasses and litter, and thorough cleaning and disinfection.

Bio-management minimizes disease pressure within the farm through vaccination, optimal nutrition, environmental management, pest control, water sanitation, litter management, and animal welfare practices.

Farm design also plays an important role in disease prevention. Poultry farms should be located away from other commercial farms, live bird markets, and migratory bird habitats. Clearly defined clean and dirty zones, all-in/all-out production systems, and adequate downtime between flocks reduce pathogen survival and transmission.
Personnel hygiene is equally critical. Farm workers should use dedicated clothing and footwear, maintain hand hygiene, comply with visitor restrictions, and receive regular biosecurity training. Similarly, feed and water must be protected from contamination through proper storage, water chlorination, and routine quality monitoring.
Rodent and insect control programmes, together with scientifically approved mortality disposal methods, further strengthen disease prevention by eliminating important sources of pathogen transmission.

Biosecurity as a Strategic Business Investment
Historically, many poultry producers regarded expenditures on sanitation, fencing, disinfection equipment, employee training, and surveillance as unavoidable operating costs. Modern poultry enterprises increasingly recognize that these expenditures are investments that protect all other farm assets.

Feed represents nearly two-thirds of total production costs. Healthy birds utilize feed more efficiently, grow faster, produce more eggs, and require fewer medications than diseased birds. Even modest improvements in feed conversion ratio can substantially increase profitability.
Strong biosecurity systems also improve market confidence. Consumers increasingly demand poultry products that are safe, traceable, and produced under high standards of animal health and welfare. Farms maintaining effective biosecurity programmes are better positioned to comply with certification schemes, quality assurance standards, and export requirements.
From a business perspective, biosecurity reduces biological risk while improving enterprise resilience. Disease outbreaks can rapidly destroy years of investment in genetics, housing, labour, and marketing. Preventive biosecurity therefore serves as a protective framework that preserves productivity, enhances competitiveness, and ensures long-term sustainability.
Modern poultry producers should therefore ask not whether they can afford to invest in biosecurity, but whether they can afford the consequences of inadequate disease prevention.

Practical Biosecurity Measures that Enhance Profitability
The success of any biosecurity programme depends on its consistent implementation at the farm level. While sophisticated infrastructure and advanced technologies can strengthen disease prevention, many highly effective biosecurity interventions are simple, practical, and relatively inexpensive. Their value lies not in high capital investment but in disciplined and continuous application.

The first line of defence is strict farm access control. Entry to poultry houses should be restricted to essential personnel, and all visitors should comply with hygiene protocols including hand sanitization, use of dedicated clothing and boots, and passage through properly maintained footbaths. Maintaining visitor records and enforcing a minimum downtime for personnel who have recently visited other poultry farms significantly reduce the likelihood of introducing infectious pathogens.
Cleaning and disinfection remain the cornerstone of disease prevention. Poultry houses, equipment, feeders, drinkers, egg trays, transport crates, and vehicles should be thoroughly cleaned to remove organic matter before applying appropriate disinfectants. Adequate downtime between production cycles allows environmental pathogen loads to decline naturally and improves the effectiveness of sanitation programmes.
Feed and water hygiene are equally important because they represent continuous sources of pathogen exposure. Feed should be procured from reliable manufacturers and stored under dry, rodent-proof conditions to prevent fungal contamination and mycotoxin development.
Drinking water should be regularly tested for microbial quality, chlorinated when necessary, and supplied through cleaned pipelines to minimize biofilm formation.
Integrated pest management also plays a critical role. Rodents, flies, beetles, mosquitoes, and wild birds serve as mechanical carriers of numerous bacterial and viral pathogens. Effective pest control, combined with scientific carcass disposal methods such as composting, rendering, or incineration, minimizes environmental contamination and pathogen persistence.
Finally, employee education is perhaps the most cost-effective biosecurity investment. Every worker should understand disease transmission pathways, recognize early clinical signs, and consistently follow standard operating procedures (SOPs). A well-trained workforce transforms biosecurity from a written protocol into a daily management culture that protects flock health and farm profitability.

Digital Transformation of Poultry Biosecurity
Rapid advances in digital technologies are revolutionizing poultry health management by shifting disease control from a reactive to a predictive approach. Precision livestock farming integrates artificial intelligence (AI), machine learning, sensor technologies, automation, and molecular diagnostics to improve disease surveillance and decision-making.

Artificial intelligence can analyse production data such as feed intake, water consumption, mortality, growth rate, and behavioural changes to detect early indicators of disease before clinical signs become apparent. Such predictive systems enable farmers to intervene promptly, thereby reducing mortality and economic losses.
The Internet of Things (IoT) has further strengthened biosecurity by enabling continuous monitoring of environmental variables including temperature, humidity, ammonia concentration, carbon dioxide, ventilation efficiency, and water quality. Automated alerts help managers respond immediately to deviations that may compromise bird health.
Computer vision systems are increasingly being used to monitor flock behaviour, feeding activity, movement patterns, and gait abnormalities. These technologies allow rapid identification of subtle behavioural changes associated with disease onset.
Molecular diagnostic tools such as polymerase chain reaction (PCR), real-time PCR, and genomic sequencing permit rapid detection of viral, bacterial, and parasitic pathogens, facilitating timely intervention. Blockchain-based traceability systems and cloud-based farm management platforms further enhance transparency, certification, and supply chain confidence.
Although digital biosecurity requires initial investment, its long-term benefits include reduced disease incidence, improved productivity, lower veterinary costs, enhanced decision-making, and increased resilience against emerging diseases.

Biosecurity Challenges and Opportunities in India
India has become one of the world’s leading producers of poultry meat and eggs, yet the country’s diverse production systems create unique biosecurity challenges. Large integrated commercial operations coexist with smallholder and backyard poultry farms, creating epidemiological interfaces that facilitate pathogen transmission.

One of the major constraints is uneven awareness regarding the economic importance of biosecurity. Large poultry companies generally maintain comprehensive disease prevention programmes, whereas many small and medium-scale producers continue to regard biosecurity as an additional expense rather than a productive investment. Financial limitations often prevent investment in essential infrastructure such as perimeter fencing, vehicle disinfection facilities, controlled farm entry, and scientific carcass disposal systems.
High poultry density in several production clusters further increases disease risk. Frequent movement of day-old chicks, feed, eggs, live birds, and farm personnel across states facilitates pathogen dissemination. Backyard poultry, live bird markets, and mixed farming systems involving ducks and other livestock also increase the risk of zoonotic disease transmission.
Despite these challenges, India possesses significant opportunities to strengthen poultry biosecurity. The country has a strong network of veterinary universities, diagnostic laboratories, research institutes, extension agencies, and progressive poultry companies capable of promoting scientific disease prevention. Government initiatives supporting livestock health, antimicrobial stewardship, digital agriculture, and the One Health approach can further accelerate adoption of comprehensive biosecurity practices.
Public-private partnerships involving industry associations, academic institutions, pharmaceutical companies, and producer organizations will be instrumental in developing practical, affordable, and scalable biosecurity solutions for Indian poultry farmers.

Biosecurity within the One Health Framework
Modern biosecurity extends beyond farm profitability to encompass animal health, public health, and environmental sustainability. The One Health concept recognizes the close interdependence of humans, animals, and ecosystems.

Effective poultry biosecurity reduces the circulation of zoonotic pathogens such as avian influenza and Salmonella, thereby protecting consumers, farm workers, and surrounding communities. Healthy flocks also require fewer therapeutic antibiotics, contributing to global efforts to combat antimicrobial resistance (AMR).
Good biosecurity practices improve waste management, reduce contamination of soil and water resources, and minimize environmental dissemination of infectious agents. Consequently, investments in poultry biosecurity generate societal benefits that extend far beyond individual farms by supporting food safety, environmental protection, and national food security.

Capacity Building and Policy Support
Infrastructure alone cannot guarantee successful biosecurity. Human behaviour remains one of the most critical determinants of disease prevention. Continuous training programmes should therefore be provided for farm owners, managers, veterinarians, technicians, and workers on disease recognition, personal hygiene, vaccination, cleaning and disinfection, pest control, mortality management, and emergency response.
Routine biosecurity audits, risk assessments, and comprehensive record-keeping systems enable producers to monitor flock performance and identify weaknesses requiring corrective action. Standard operating procedures should be regularly reviewed and updated in response to emerging disease threats and technological developments.
Government agencies also have an essential role in strengthening national biosecurity through veterinary services, laboratory networks, surveillance systems, science-based regulations, and financial incentives that encourage producers to invest in preventive infrastructure. Harmonization of national standards with international guidelines will further improve India’s competitiveness in global poultry trade.

Way Forward
Biosecurity has evolved from a routine veterinary recommendation into one of the most valuable strategic investments in modern poultry production. Scientific evidence consistently demonstrates that prevention delivers substantially greater economic returns than treatment. Every investment made in disease prevention safeguards valuable biological assets, preserves productivity, reduces veterinary expenditure, minimizes antimicrobial use, and enhances market confidence.
For India, where poultry production continues to expand rapidly, widespread adoption of comprehensive biosecurity systems will be fundamental to sustainable growth. Success will require coordinated efforts involving producers, veterinarians, researchers, policymakers, industry organizations, and technology providers working within a One Health framework.
The future of poultry farming will increasingly depend on predictive health management supported by digital technologies, precision farming, artificial intelligence, and robust surveillance systems. Producers who integrate biosecurity into their core business strategy will be better equipped to withstand emerging disease threats, satisfy evolving consumer expectations, and compete successfully in international markets.
Ultimately, the most profitable poultry enterprise is not the one that spends the least on disease prevention, but the one that invests wisely to ensure disease never compromises productivity. Biosecurity should therefore be regarded not as an operational expense but as a high-return investment that protects animal health, public health, environmental sustainability, and the long-term resilience of the poultry industry.

Selected References
1. Alexander, D. J. (2007). An overview of the epidemiology of avian influenza. Vaccine, 25, 5637–5644.
2. FAO. (2023). Good Practices for Biosecurity in the Poultry Sector. Food and Agriculture Organization of the United Nations.
3. Gelaude, P., Schlepers, M., Verlinden, M., et al. (2014). Measuring on-farm poultry biosecurity using Biocheck.UGent. Poultry Science, 93, 2740–2750.
4. Glisson, J. R., Hofacre, C. L., & Christensen, J. P. (2019). Poultry Diseases. Elsevier.
5. WOAH. (2023). Terrestrial Animal Health Code.
6. Swayne, D. E. (Ed.). (2020). Diseases of Poultry (14th ed.). Wiley-Blackwell.
7. World Health Organization. (2022). One Health Joint Plan of Action (2022–2026).
8. World Bank. (2022). One Health Operational Framework for Strengthening Animal Health Systems.
9. FAO. (2022). Biosecurity Guide for Poultry Production and Value Chains.
10. USDA APHIS. (2023). Defend the Flock: Biosecurity for Poultry Owners.

Nuance Biotechnology, a rapidly emerging player in the feed additives industry, has made significant strides in 2024 by acquiring two prominent French companies—Global Nutrition International and NutriConcept. This strategic move has bolstered their global footprint, expanded R&D capabilities and facilitated their entry into key markets, including India. Poultry Creations, along with other poultry media, had the privilege of speaking with Dr. Nemanja Todorovic, Chief Business Officer and Mr. Joginder Singh Uppal, Business Director, South Asia, during the 35th AGM of the Poultry Federation of India in Gurugram to discuss their vision, innovations and plans for the Indian market

Entering the Indian Market and Expansion Strategies:

When did Nuance Biotech enter the Indian market and what are your strategies for expansion?
Dr. Nemanja Todorovic: India is not just a country; it is a continent in itself with immense potential in biotechnology and livestock. Recognizing this, we have appointed knowledgeable professionals like Mr. Uppal to lead our initiatives. Our key strategies include:
1. Forging strategic partnerships with key industry players.
2. Expanding distribution networks for broader market penetration.
3. Collaborating with research institutions to localize our products.
4. Educating farmers on the benefits of postbiotics and other innovations tailored to Indian conditions.”

Joginder Singh Uppal: “We launched our South Asian operations in June 2024 with a strong focus on poultry and dairy. Our flagship products, Nu.biom Aves for poultry and Nu.biom Bos for dairy, enhance resilience, performance and farm profitability. Our goal is to empower farmers through innovative solutions backed by scientific research and technical expertise.”

Understanding Postbiotics

Question: Can you explain the difference between postbiotics and other types of biotics?
Dr. Nemanja Todorovic: “Biotics are broadly categorized into prebiotics, probiotics, and postbiotics:
1. Prebiotics serve as a nutrient source for beneficial gut bacteria.
2. Probiotics are live microorganisms that improve gut health.
3. Postbiotics are metabolic byproducts of probiotics, offering stable and targeted benefits without the viability concerns of probiotics.

Our postbiotics enhance gut microbiota balance, optimize nutrient utilization and contribute to immune modulation. Imagine prebiotics as soil, probiotics as rice growing in the field and postbiotics as rice noodles ready for consumption.”

Tailoring Solutions for the Indian Market

Question: How does Nuance Biotech cater to the unique needs of the Indian market?
Joginder Singh Uppal: “We offer tailored solutions to address challenges in poultry and dairy farming, such as:
Postbiotics: A novel concept with proven benefits for immunity, egg quality and overall productivity.
Global Biotics: Products like mycotoxin binders (e.g., Global Fix) and acidifiers that address vital industry concerns.

Our goal is to support farmers with innovative products backed by research, while also educating them about sustainable and profitable farming practices.”

Market Strategy and Customer Engagement

Question: Who is your primary target in the market—feed mills, breeders, GP operators, commercial broiler farmers or integrators?
Joginder Singh Uppal: “Our primary focus is on feed mills since our products are predominantly feed additives. About 60-70% of the industry relies on feed, making this our initial target. Our secondary focus is integrators and large-scale farmers, including layer farmers who produce their own feed. Products like NutriGut and Globacid DW are designed for these segments.”

Unique Selling Proposition and Market Entry

Question: With several toxin binders and acidifiers in the market, what makes your products stand out?
Dr. Nemanja Todorovic: “Our precision production technology sets us apart. From raw material selection and fermentation to production and quality control, every step is meticulously executed. Our R&D-driven approach ensures high efficacy. Global Nutrition, part of our portfolio, has been a trusted name since 2002, exporting to over 40 countries. This global presence underscores the reliability and effectiveness of our products.”

Question: Have your products been introduced to the Indian market yet?
Dr. Nemanja Todorovic: “We commenced operations in mid-2024, focusing on key partnerships and collaborations. Our first consignment is scheduled to arrive next month, allowing us to engage with clients and initiate trials. Discussions with several companies are already underway.”

Future Innovations and Long-Term Vision

Question: Can you share upcoming innovations or product launches for the Indian poultry sector?
Joginder Singh Uppal: “Our focus extends beyond product launches—we provide integrated solutions. Enhancing animal resilience is at the core of our philosophy. By leveraging our expertise in microbial metabolites, we develop solutions tailored to specific market needs. While poultry and dairy remain our primary sectors, we are continuously evolving to address industry challenges.”

Question: What are your long-term plans for the Indian market?
Dr. Nemanja Todorovic: “Our strategy is structured around three key phases:
1. Establishing Partnerships – We have made significant progress in forging valuable collaborations.
2. Regional Expansion – In addition to India, we are targeting Pakistan, Bangladesh, Nepal and Sri Lanka.
3. Direct Sales and Marketing – While working with distributors for outreach, we also plan to engage directly with key accounts representing 50-60% of the poultry industry.”

Sustainability and Industry Challenges

Question: What steps is Nuance Biotech taking to ensure product sustainability?
Dr. Nemanja Todorovic: “Sustainability is at the core of our innovation strategy. We focus on enhancing nutrient utilization, reducing waste and minimizing environmental impact. For example, our solutions target ammonia control in poultry and aquaculture. Additionally, our postbiotic solutions have shown promise in reducing methane emissions in dairy cattle, and we plan to conduct further trials in India with leading research institutions.”

Question: Unlike poultry, the Indian dairy sector consists largely of unorganized small farmers. How does Nuance Biotechnology plan to support them?
Dr. Nemanja Todorovic: “About 80% of India’s dairy farmers operate at a small scale. We aim to reach them through a three-pronged strategy:
1. Strengthening our distribution network to enhance accessibility.
2. Focusing on large dairy operations that drive significant market influence.
3. Leveraging veterinary shops as a direct channel for small-scale farmers, a model that has succeeded in similar markets.”

In conclusion, Nuance Biotech is positioning itself as a pioneering force in the feed additives sector, committed to innovation, sustainability and farmer education. As they expand their presence in India and beyond, their solutions promise to enhance efficiency, profitability and resilience in the livestock industry.

Emerging Technologies in Poultry Litter Management: Enhancing Sustainability and Efficiency in Poultry Production

Efficient poultry litter management for broiler chicken farms is essential for maintaining bird health, ensuring farm profitability, and protecting the environment. One key tool in this effort is the Poultry Litter Decision Support System (PLDSS), which outlines a five-step plan for effective litter management. Additionally, a temperature prediction model can aid in litter pasteurization, further enhancing its efficacy. Innovative technologies such as electronic noses and AI-powered robots are being employed to address challenges related to odor control and litter management tasks. Moreover, the use of artificial turf flooring is showing promise in improving air quality within laying hen houses.

Keywords: Poultry litter management, PLDSS, litter pasteurization, e-nose, AI robots, artificial turf flooring

The poultry industry’s phenomenal growth creates a critical challenge: managing the vast amount of poultry litter, a mix of manure and bedding materials. The intricate interplay among the poultry industry’s worldwide impact, technical advancements, and the urgent demand for innovative approaches to litter reduction are significant factors compelling us to consider litter management.

With the United States leading the way in broiler production, the global output reached a staggering 101.2 million metric tons in 2021.This exponential growth necessitates sustainable practices to handle poultry litter efficiently. As the poultry industry continues to expand, effective waste management becomes paramount.
The amount of chicken manure produced globally is astounding. The amount of broiler meat produced in 2021 was estimated to be 101.2 million metric tons; by 2023, that amount is expected to increase to 103.4 million. About 1.1 to 2.4 MT of dry manure, 7.3 to 12.7 MT for turkeys, and 3.9 MT for ducks are produced by 1000 birds raised to market age on commercial farms. 9486 MT of hatchery waste, 1.74 million MT of slaughterhouse waste, and 38.33 million MT of chicken manure were produced in India in 2018–2019. To properly manage the waste from poultry, this exponential growth calls for sustainable practices.

Not only is efficient litter management important for the environment, but it’s also essential for farm productivity and animal welfare. Litter management that is done right enhances bird health, productivity, and profitability. However, poor handling can result in disease outbreaks and significant financial losses.

Poultry Litter Decision Support System (PLDSS)
Applying chicken manure to row crops and pastures is an inexpensive substitute for synthetic fertilizers. Because of the high P to N ratio in chicken litter, applying it in accordance with the agronomic N requirements of the fodder has over time led to a buildup of P in the soil. P runoff can hasten eutrophication, which can seriously degrade water bodies that support aquatic, recreational, and drinking water uses, despite P being a necessary nutrient for plant growth. There are numerous definitions for a DSS. But it can be thought of as an interactive, adaptive, and flexible computer-based information system designed specifically to help identify and resolve a complex, poorly organized, or unstructured.

The Poultry Litter Decision Support System (PLDSS) is a comprehensive five-step management plan that begins by estimating farm-produced poultry litter and compost, assessing their nutrient content for proper application. It then identifies suitable land for spreading, aligns application with crop nutrient needs, and manages excess litter by exploring responsible disposal options. Over time, the PLDSS can create a database to aid research on non-point source pollution and inform businesses about surplus litter for value-added products, offering a holistic view of poultry litter management challenges.

Litter Temperature Prediction Model & Pasteurisation Decision Support Tool
The model was created using a data set that included 542 temperature profiles taken at different depths during a litter pasteurization cycle that lasted six to ten days in about 100 litter heaps that were treated on eight farms. There are more than 90,000 distinct temperature records in the data collection. Using 75% of the data for development and 25% for validation, an empirical model of the dataset was created.

As part of the chicken CRC project Methods to quantify and inactivate viruses in chicken litter, a litter temperature prediction model and a pasteurization decision assistance tool were created. The tool’s parameters are listed in the following. Purpose of this tool is to forecast temperatures and offer user-defined summary temperature data for poultry broiler litter that has been heaped for pasteurization.

A sectional heat map of the heap/windrow at a given time with a table showing the percentage of the heap in different temperature classes, average, minimum, and maximum heap temperatures, the proportion of the heap/windrow reaching specified temperatures and durations, and temperature profiles at specified depths.

Animal Waste Management Software
Software for animal waste management (AWM) is a tool for planning and designing projects that supports the calculations needed for manure management systems. Lagoon, storage pond, storage tank, and stacking facility design is supported by the expected daily production of manure, bedding, and process water. Average monthly precipitation and evaporation statistics are utilized in the AWM methods and computations, which are based on data from the AWMFH. Additionally, the program encourages the design of multiple-cell anaerobic and aerobic lagoons that can be used alone or in conjunction with other manure storage facilities. Users of the program can produce preconfigured reports for design, operation, and maintenance. Design variables that are integrated into the report templates can be used to create customized reports. Manure Master, a streamlined tool for calculating the amount of cropland required to create the nutrients generated by an animal feeding operation, is also included in AWM. The nitrogen, phosphorous, and potassium content of the manure and the amount of these nutrients utilized by crops are combined to create a gross nutritional balance that is calculated by Manure Master. This balance can be calculated based on known recommended fertilizer application rates, or it can be estimated based on the nutrient content of the plant. The nitrogen balance is calculated with the expected losses from leaching, denitrification, and volatilization.

Artificial Turf Floor
Artificial turf flooring has the potential to significantly improve the air quality in laying hen houses, according to studies. Artificial turf drastically lowered ammonia, carbon dioxide, and particle sizes when compared to regular wood shavings. The reasons for this progress are several. First off, artificial turf reduces ammonia generation directly by preserving more nitrogen and lowering the pH of manure.

Secondly, by reducing sources on the floor where hens interact, the turf itself lowers airborne particulate pollution. Lastly, it appears that artificial turf affects airflow patterns, which results in a more uniform gas distribution and a decrease in concentration gradients inside the housing. It’s vital to remember that proper comparisons of air quality between various flooring types depend on maintaining stable and regular ventilation rates.

Electronic Nose
Effective poultry litter management involves addressing odor issues associated with poultry waste. Traditional olfactometry, while valuable, can be costly due to sample collection and analysis expenses. To overcome these limitations, electronic noses (e-noses) offer an affordable and real-time alternative. E-noses detect volatile organic compounds (VOCs) linked to odors, providing accurate measurements. Integrating e-noses alongside traditional methods allows poultry farmers to make informed decisions, minimize odors, and maintain a healthier environment for both birds and humans.

AI-Powered Robots for Litter Management
Numerous businesses have created robots to assist in managing the litter in broiler homes for chickens. For instance, Octopus Robots, a French business, has introduced two fully autonomous robots, one of which is intended to turn and aerate chicken bedding. A different business, Metabolic Robots, has developed a robot that can oversee, measure, monitor, and regulate operations on chicken farms. These robots can grind, mix, aerate, tilt, decake, scare, and pulverize poultry litter. The effectiveness of litter management in chicken broiler houses can be increased with the employment of these robots.
The AI-driven autonomous robots are meant to clean the litter in chicken broiler houses. It has a scarifier installed to aerate the litter once a day, preventing crusting and enabling reduced ammonia levels. In the chicken shed, the robot is also capable of gathering data on temperature, humidity, and ammonia levels. AI-powered robots can not only scarify the litter but also carry out other duties like drying the litter, preventing scab development, lowering ammonia generation, distributing sanitizing solutions, and cleaning the litter by misting sanitizing solutions. The robot has the ability to administer local adaptive therapy and disperse itself as near to the target as it can.
Robots using artificial intelligence (AI) are useful and effective technologies for controlling litter in chicken broiler facilities. Their capacity for multitasking on their own can enhance litter control effectiveness and promote a healthier environment for the chickens. Emerging technologies offer a beacon of hope. Precision livestock farming and waste-to-energy processes are just a few examples of innovative solutions that can minimize environmental impact, enhance resource utilization, and safeguard animal and human health.

References :
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