Introduction

Why it matters in modern poultry production
– Rapid multiplication of Eimeria can produce substantial intestinal injury within a short period.
– Subclinical coccidiosis may reduce feed efficiency, growth and flock uniformity without dramatic clinical signs.
– High oocyst contamination of litter increases exposure and repeated infection pressure.
– Effective control requires attention to parasite biology, farm management and appropriate anticoccidial programmes.

Etiology
Seven major Eimeria species are recognized in chickens. E. acervulina and E. maxima are frequently encountered, while E. tenella is particularly pathogenic and associated with severe caecal disease and haemorrhage (Yaqub et al., 2023). Species differ in preferred intestinal sites, lesion patterns and pathogenicity.

Transmission
The principal route is faecal–oral transmission. Birds ingest sporulated oocysts from contaminated litter, feed, water, equipment or the environment. Moisture, oxygen and suitable temperature favour sporulation, allowing infective oocysts to accumulate and maintain the infection cycle (Pal et al., 2023).
Life Cycle of EIMERIA

Ingestion of sporulated oocysts → release of sporozoites → epithelial invasion → multiplication → gamete formation → oocyst formation → faecal shedding → environmental sporulation.

Clinical Signs
Severity depends on Eimeria species, infective dose, bird age, immunity and environmental management. Signs include reduced feed intake, depression, ruffled feathers, drooping wings, enteritis, diarrhoea or dysentery, poor growth and increased mortality in severe cases (Pal et al., 2023).
– Reduced body-weight gain and flock uniformity
– Poor feed conversion and production performance
– Diarrhoea or blood-stained droppings in severe infections
– Dehydration, weakness and depression
– Mortality when tissue damage and blood loss are extensive
Species-specific sites

Post-Mortem Lesions
Post-mortem examination helps identify likely Eimeria species and estimate the distribution and severity of intestinal damage. Lesion patterns should be interpreted with clinical findings, litter condition, performance data and, where appropriate, laboratory diagnosis (Pal et al., 2023; Yaqub et al., 2023).

Key lesion patterns

Prevention and Control
Effective control integrates anticoccidial programmes with litter management, hygiene, stocking-density control, ventilation and sound flock management. Continuous or inappropriate use of a single anticoccidial can contribute to reduced efficacy and resistance selection; rotation, shuttle programmes, combinations and vaccination are among approaches used for longer-term control (Usman et al., 2011; Chapman, 2017; Noack et al., 2019).

Anticoccidial programmes
– Rotation changes the active ingredient or mode of action between production cycles.
– Shuttle programmes use different anticoccidial strategies during different feed phases.
– Combination programmes can broaden anticoccidial activity and may help address reduced sensitivity when appropriately designed (Chapman & Rathinam, 2022).
– Vaccination can provide controlled exposure to selected Eimeria strains and support protective immunity.

Ionophore vs Chemical

Combination programmes
Combining compatible anticoccidial activities can broaden control and reduce dependence on a single mode of action. Programme selection should consider disease pressure, previous anticoccidial history, susceptibility patterns, compatibility and label requirements (Chapman & Rathinam, 2022).

STALLEN’S DUAL APPROACH TO COCCIDIOSIS CONTROL
Stallen South Asia offers a dual approach to coccidiosis management with Manacox Plus, bringing together ionophore and chemical anticoccidial activity in one formulation. This approach is designed to support practical, structured coccidiosis-control programmes while reducing dependence on a single mode of action.

MANACOX PLUS
Manacox Plus is a dual-active anticoccidial formulation combining an ionophore and a chemical anticoccidial. It contains Monensin Sodium 8% + Nicarbazin 8% for practical coccidiosis prevention programmes in broilers.
Key Product Points

WHY A DUAL APPROACH
Using monensin sodium together with nicarbazin brings ionophore and chemical anticoccidial activity into one formulation. This can fit structured prevention programmes where the objective is effective control without unnecessary reliance on a single mode of action. Use should follow the approved label and veterinary guidance.
Practical use
– Use within a planned farm coccidiosis-control programme.
– Maintain good litter quality, ventilation, stocking density and drinker management.
– Review anticoccidial history and flock response when planning future programmes.
– Follow approved dose, withdrawal period and compatibility instructions.

References are available on request.

Introduction

Gut: The First Line of Immune Defence
The intestinal defence system consists of several interconnected components, including the mucus layer, intestinal epithelial cells, tight junctions, antimicrobial substances, gut microbiota and gut-associated lymphoid tissue (GALT).

The epithelial cells form a physical barrier between the intestinal contents and the internal tissues. Tight-junction proteins such as occludin, claudins and ZO-1 regulate the movement of substances between epithelial cells. The mucus layer provides an additional protective environment, while immune cells located within and beneath the intestinal mucosa continuously monitor microbial and dietary antigens.
Thus, the intestine acts as both a selective absorption system and an immune surveillance system.

Gut Microbiota and Immune Development
The intestinal tract contains a complex microbial ecosystem. A balanced microbial population can contribute to pathogen exclusion, production of microbial metabolites, maintenance of intestinal integrity and modulation of host immune responses.
Beneficial microorganisms and their metabolites communicate with intestinal epithelial cells and immune cells. Among these metabolites, short-chain fatty acids (SCFAs) such as acetate, propionate and butyrate are particularly important because they can influence epithelial health, immune-cell activity and inflammatory responses. Therefore, gut microbiota and immunity have a bidirectional relationship. A healthy microbiota supports a healthy intestinal barrier and balanced immune signalling. At the same time, the immune system regulates microbial populations and helps maintain intestinal homeostasis.
What Happens When Gut Health Is Compromised?
Commercial poultry are exposed to several factors capable of disturbing gut integrity, including coccidiosis, bacterial pathogens, mycotoxins, heat stress, poor water quality, nutritional imbalance and dysbiosis.

A compromised gut can result in epithelial damage, disruption of tight junctions, increased intestinal permeability, inflammation and oxidative stress, altered immune response and reduced performance. This process is sometimes described as increased “intestinal permeability” or “leaky gut.”

When intestinal integrity is compromised, nutrients may not be utilized efficiently and microbial products can interact more extensively with host immune mechanisms. The bird may consequently spend additional nutrients and metabolic resources on inflammation and tissue repair rather than growth or egg production.

Coccidiosis, Mycotoxins and Heat Stress

Coccidiosis is a classic example of the gut–immune relationship. Eimeria infection damages intestinal epithelial cells, alters intestinal morphology and stimulates an inflammatory and immune response. Consequently, coccidiosis control is not only a parasite-management issue but also a gut health, nutrition and immune-management issue.

Similarly, mycotoxins can affect intestinal integrity, oxidative status, microbial balance and immune function. Their impact may therefore extend beyond the feed itself to the overall gut–immune axis.

Heat stress is particularly important in tropical poultry production. Heat stress can alter feed intake, intestinal physiology, microbial balance and barrier integrity, potentially increasing inflammatory and oxidative stress. Maintaining gut integrity during heat stress is therefore an important component of maintaining flock resilience.

Gut Health and Vaccine Response
An effective vaccination program depends on the bird’s ability to recognize antigens and develop appropriate humoral and cellular immune responses. This requires adequate availability of energy, amino acids, vitamins, minerals and antioxidants. Therefore, gut health indirectly supports the nutritional foundation required for immune responses. A healthy intestine facilitates nutrient digestion and absorption, while intestinal inflammation or damage can increase nutrient requirements for tissue repair and immune activity. It is important, however, to recognize that good gut health alone does not guarantee vaccine success. Vaccine quality, administration, maternal immunity, biosecurity, disease pressure, nutrition and environmental conditions also influence the final immune response.

Nutritional Support for the Gut–Immune Axis
Nutrition is one of the most important tools for supporting the gut–immune relationship. Zinc contributes to epithelial integrity, cellular proliferation, enzyme activity and immune-cell function. Selenium is an important component of antioxidant defence systems and supports cellular protection and immune function. Vitamins A and E also contribute to mucosal integrity, antioxidant protection and immune responses.
Nutritional interventions such as probiotics, prebiotics, postbiotics, organic acids, enzymes, yeast-derived products, MOS and β-glucans may be used as part of integrated gut-health programs. MOS can support gut health through microbial interactions and pathogen-exclusion mechanisms, while β-glucans can interact with innate immune pathways and influence immune-cell activity. However, responses depend on product source, structure, dose, bird age, diet and challenge conditions; therefore, these products should be evaluated based on scientific evidence and field performance rather than assuming that all products have identical effects.

Practical Approach for Commercial Poultry
A successful gut-health program should not depend on a single feed additive. It should combine:
– High-quality and properly stored feed
– Regular mycotoxin monitoring and management
– Good drinking-water quality and sanitation
– Effective coccidiosis control
– Appropriate vaccination and biosecurity
– Heat-stress management
– Balanced amino acid, vitamin and mineral nutrition
– Appropriate use of probiotics, prebiotics/postbiotics and other gut-health products
– Monitoring of litter quality, feed intake, FCR, mortality and flock uniformity

Conclusion
The gut and immune system should be viewed as two interconnected components of the same biological defence network. A healthy intestinal microbiota, intact epithelial barrier and properly functioning GALT provide the foundation for balanced immune development and response. For commercial poultry, the concept is simple: “Protect the gut to support immunity, and support immunity to maintain flock resilience.”
Gut health is therefore not only about digestion and FCR. It is closely connected with nutrient utilization, immune development, disease resistance, vaccine responsiveness and ultimately flock productivity.
The future of poultry nutrition will increasingly focus on managing the gut–microbiota–immune axis through integrated nutrition, health and farm-management strategies rather than addressing individual problems in isolation.

The meeting commenced with an introductory address by Mr. Deepak Khosla, General Manager (Marketing), who welcomed the participants and highlighted the company’s commitment to delivering science-based solutions for the poultry industry.

Dr. Prakash Reddy, DGM (Technical), delivered a currently relevant and focused presentation on “Hatchery Vaccines and Vaccination: Catching the Future”. He emphasized on the emergence of pathogens which are critical for designing effective control strategies because it reveals key vulnerabilities, transmission dynamics (vertical), and potential immune evasion mechanisms. Highlighted the emerging vaccine technologies opening new fields of possibilities for disease control and disease management, which include genotype based vaccines, vector vaccines, immune complex vaccine etc. The novel vaccine technologies would likely impose completely novel immune pressure or selection for resistance with enhanced immunosuppression and changes in patterns of antigenic variation, tissue tropism, and invasion pathways, so should be selective. Lastly, he updated the Innovative hatchery vaccination methods adapted in India for mass administration with speed and accuracy with ease of adaptation of semi-automated subcutaneous vaccination, spray vaccination etc. in day old chicks with a check on vaccinal reactions, errors and miss outs.

The second session, “Improving Broiler Performance through Effective Water Sanitation and Precise Medication Dosing,” was presented by Dr. Datta Kulkarni, DGM (Technical). He discussed how good water quality, effective sanitation, and accurate medication dosing can help enhance broiler health, performance, and farm profitability.

The programme concluded with valuable remarks from Mr. H. S. Padda, DGM, (Marketing), who underlined the importance of adopting scientific and practical approaches to address emerging poultry health challenges. Mr. Shashi Bhushan, AGM, (Marketing), delivered the vote of thanks and expressed gratitude to the speakers and participants for making the meeting informative and successful.

The technical meeting reaffirmed Ventri Biologicals’ commitment to advancing poultry health through knowledge sharing, innovation, and effective field-level solutions.

Zamira brought together its South Asia team, global leadership and key partners for its Annual Kick-Off Meeting, held from 28–30 July 2026 at Aamby Valley, Lonavala. Under the theme “One Team, One Goal,” the three-day event provided an opportunity to reflect on the achievements of the past year, align priorities for FY27 and strengthen the capabilities and partnerships supporting Zamira’s continued growth across South Asia.

Zamira CEO Stewart Cairns travelled from Australia to open the meeting, reviewing the key drivers behind the previous year’s performance and outlining areas of focus for the year ahead.

“South Asia plays a vital role in Zamira’s global success. The dedication of our local team, combined with the strength of our partnerships, continues to set the standard for what ‘One Team, One Goal’ truly means,” Mr Cairns said.

Dr Shaveta Sood, Director South Asia, then presented the FY27 goals and priorities, setting the direction for the team for the coming year.

The program also focused strongly on the commercial, marketing and technical capabilities required to support these objectives. Dr Shailaja Rajyam, Product and Marketing Manager, presented Zamira’s marketing and new product plans, including the marketing communications that will support upcoming product introductions.

Investment in people and capability development was another key focus of the meeting. Agribusiness specialist David Faulkner and Zamira Global Trainer Jane Enciso delivered an advanced sales training program, providing the team with practical tools and strategies to strengthen customer engagement and sales performance.

A dedicated leadership development program for people managers also explored the skills and behaviours required to develop future-ready sales leaders and support the continued growth of Zamira’s people from within the organisation.

Technical learning formed an important part of the program, with Dr Sujit Kulkarni of Bextral, Netherlands, presenting on the technical aspects of ZamiBoost Immune Defence Liquid. The session provided the team with further technical insights to support informed discussions with customers.

The Kick-Off concluded on 30 July with Zamira’s Channel Partners Forum, recognising the important contribution of the distribution and strategic partners who support the company across the region. Partners received commemorative mementos bearing the message “Zamira Celebrating 16 Years of Excellence” in recognition of their loyalty and continued partnership.
The evening also celebrated the achievements of the Zamira South Asia team, with awards recognising outstanding contributions across both sales and support functions. The awards reflected the teamwork, commitment and shared purpose at the heart of this year’s theme.

Closing the event, Dr Shaveta Sood acknowledged the contribution of Zamira’s people and partners to the company’s continued progress in South Asia.

With its people, partners and priorities aligned for FY27, the Annual Kick-Off reinforced the message at the centre of Zamira’s plans for the year ahead: One Team, One Goal.

Yet despite the widespread use of organic trace minerals (OTMs), one important misconception continues to exist in the industry: that all organic trace minerals are the same.

Looking Beyond Inclusion Levels
When evaluating trace mineral programs, discussions often focus on inclusion rates, mineral concentration, and cost per ton of feed.

However, the true value of a trace mineral is not determined simply by how much is added to a formulation. Rather, it is determined by how much of that mineral is available for absorption and utilization by the bird. This distinction becomes increasingly important in modern poultry production.

Many producers experiencing challenges like, inconsistent performance, reduced meat quality, or variability in the flock focus on nutrient inclusion. Yet nutrients can only contribute to biological functions if they successfully reach the absorption sites where they are needed.

As poultry genetics continue to advance, nutritional efficiency has become just as important as nutritional adequacy. This shift is causing nutritionists to move beyond a simple question of: “How much mineral is in the feed?” to a more important question: “How much mineral is actually available to the bird?”

Understanding the Challenge: Mineral Antagonism
Trace minerals perform important functions throughout the bird’s body. Zinc, copper, and manganese act as cofactors for numerous enzymes involved in bone formation, connective tissue development, collagen synthesis, skin integrity, antioxidant defense, and immune function.

However, the digestive tract is a highly complex environment. As minerals move through digestion, they encounter changes in pH and interactions with dietary compounds such as phytate, fiber components, and even other minerals. These interactions can reduce mineral availability before absorption occurs.

This phenomenon, referred to as mineral antagonism, helps explain why increasing mineral inclusion does not always result in improved mineral utilization. Simply feeding more minerals does not necessarily mean the bird receives more minerals. In many situations, the challenge is not supply. The challenge is bioavailability.

Dietary antagonisms can reduce mineral availability before absorption occurs, limiting nutrient utilization despite adequate inclusion levels

Organic Trace Minerals: A Category, Not a Chemistry
To help improve mineral bio-availability, the industry increasingly adopted organic trace minerals. However, the term “organic trace mineral” can create confusion. Some assume that all OTMs provide similar benefits because they belong to the same category. In reality, organic trace minerals represent a broad group of products that may differ substantially in:
· Ligand type
· Ligand-to-mineral ratio
· Molecular structure
· Bonding characteristics
· Electrical charge of the molecule
· Stability in Upper Digestive Tract
These differences influence how minerals behave in the gastrointestinal tract and how effectively they remain available for absorption. In other words, two products may both be labelled as organic trace minerals while functioning very differently inside the bird.

Why Chelation Matters
Among organic trace minerals, one class stands out from the others: bis-chelates. The word chelate originates from the Greek word chela, meaning crab claw or pincer. Similar to two crabs holding a metal securely giving it the maximum protection a Chelate forms when a ligand connects to a metal atom at more than two points. A 2 five member rings connected to the metal with two points of contact is the most stable complex found in nature. This structure helps provide protection compared with less defined mineral associations. However, not all organic trace minerals are true chelates. True chelates require a neutral charge to protect the mineral and enhance stability. Not all organic trace minerals (OTMs) provide a neutral charge; therefore, not all OTMs are true chelates. Some products are better described as complexes, proteinates, or other association forms. While they are still classified as organic trace minerals, they can differ significantly in chemical stability and behavior during digestion. The degree of protection provided by the mineral structure ultimately determines how vulnerable the mineral may be to antagonistic interactions.
Differences exist among chelates, too. There are chelates where one ligand is bound to the metal and then there are bis-chelates where two ligands are bound, creating a neutral charge and making the molecule less susceptible to antagonism. (see image)

Why Molecular Structure Matters
Research continues to demonstrate that mineral structure influences stability and bio-availability. When minerals dissociate during digestion, they become charged ions that are more likely to interact with negatively charged compounds such as phytate, fiber complexes and other minerals. These interactions can reduce availability before absorption occurs.

For this reason, increasing attention is being given to mineral structures specifically designed to maintain stability throughout digestion. One such approach is bis-chelation technology.

Bis-chelated trace minerals are characterized by a defined molecular structure consisting of one mineral ion bound to two ligands, creating two stable chelate rings. This unique architecture helps maintain structural integrity while moving through the digestive tract.
An equally important feature is their neutral molecular charge. Because neutrally charged molecules are less likely to participate in unwanted interactions, the structure helps protect the mineral, reducing opportunities for antagonism and supporting mineral availability until absorption occurs.

Bis-chelated trace minerals feature a defined molecular structure designed to support stability and mineral availability during digestion.

The Future of Trace Mineral Nutrition
As poultry production evolves, mineral nutrition must evolve with it. The industry’s next opportunity may not come from increasing mineral inclusion rates but from improving how effectively minerals are utilized by the bird. This requires looking beyond product categories and focusing on the scientific characteristics that influence mineral availability. Organic trace minerals can provide significant advantages over traditional inorganic sources. However, not all organic trace minerals are created equal. Their molecular structure matters. Their stability matters. And ultimately, their ability to deliver minerals to the animal matters.

As nutritionists continue searching for ways to improve performance consistency, skeletal integrity, meat quality, and return on investment, bis-chelated trace minerals are an increasingly important technology because they combine defined structure, enhanced stability, and optimized bioavailability into a scientifically designed mineral solution.

Contact your local NOVUS representative to learn more about bis-chelated trace minerals from the company that brought the technology to the animal agriculture industry over 20 years ago.

PL Agro Technologies Pvt. Ltd. is Now ZAGRO India Pvt. Ltd.

Strengthening the ZAGRO Group’s Commitment to Animal Health, Animal Nutrition and Crop Care in India

Chennai, India — July 2, 2026

PL Agro Technologies Pvt. Ltd., a wholly owned subsidiary of ZAGRO Singapore Pte. Ltd., has officially rebranded as ZAGRO India Pvt. Ltd. The change deepens the company’s integration with the ZAGRO Group — a global provider of Animal Health, Animal Nutrition, Crop Care, Public Health, and Industrial Chemicals with over 70 years of international experience.

The new identity aligns the Indian business with ZAGRO’s global brand, giving customers access to stronger R&D, global manufacturing standards, and a broader product portfolio — while preserving the same trusted relationships, service, and quality customers rely on today.

Investing in India’s Growth

India remains one of the world’s fastest-growing agricultural and livestock markets. As ZAGRO India, the company is expanding across three core segments:

• Animal Nutrition — vitamin & mineral premixes, specialty feed additives, toxin binders, functional nutrition solutions
• Animal Health — poultry, swine, dairy and aquaculture solutions, plus farm biosecurity programs
• Crop Care — crop protection, plant nutrition, specialty agri-chemicals, and sustainable production technologies

The company continues to invest in its Chennai, Tamil Nadu manufacturing facility and technical teams, maintaining stringent international quality standards while tailoring solutions to local farming conditions.

A Message from Management

“This transition represents far more than a name change. It reflects our commitment to becoming an even stronger partner for Indian agriculture by leveraging ZAGRO’s global expertise, innovation, and quality standards — delivering solutions that improve animal health, farm productivity, and sustainable agriculture across India.”

 What Stays the Same

• Ownership under the ZAGRO Group
• Existing contracts, commitments, and customer relationships
• Product quality and service standards
• Our experienced management and technical teams

Looking Ahead

With the full strength of the ZAGRO Group behind it, Zagro India is positioned to become a leading provider of integrated animal health, animal nutrition, and crop care solutions — supporting poultry, dairy, beef cattle, swine, aquaculture, companion animal, and crop production customers nationwide with technical consultancy, product support, and training.

About ZAGRO India Pvt. Ltd. A wholly owned subsidiary of ZAGRO Singapore Pte. Ltd., ZAGRO India delivers innovative Animal Nutrition, Animal Health, and Crop Care solutions, combining global expertise with local market knowledge to enhance livestock productivity, crop performance, and sustainable agriculture.

About ZAGRO Singapore Established in 1953, ZAGRO Singapore Pte. Ltd. is a leading agribusiness group operating in over 70 countries, developing, manufacturing, and marketing Animal Health, Animal Nutrition, Crop Care, Public Health, and Industrial Chemical products worldwide.

Contact
ZAGRO India Pvt. Ltd.
(Formerly PL Agro Technologies Ltd.)
Chennai, Tamil Nadu, India

Manas Mitra, Commercial Head -India
manas.mitra@zagro.com
Website: www.zagro.com

FERMNUTRAL: A POSTBIOTIC INNOVATION TO MAXIMIZE GUT HEALTH AND EFFICIENCY IN POULTRY PRODUCTION

Gut Health: The Key to Modern Poultry Production
The expression of the genetic potential of poultry largely depends on intestinal health. The gastrointestinal tract houses nearly 70% of the immune cells and constitutes the primary barrier against enteric pathogens. However, during the early stages of life, immune immaturity increases susceptibility to infections and microbiota imbalances, particularly under intensive production systems.

Traditionally, antibiotic growth promoters (AGPs) have been used to improve productive performance and reduce health-related challenges. However, their continuous use has been associated with antimicrobial resistance, intestinal dysbiosis, and concerns regarding food safety and public health.

In this context, postbiotics have emerged as a sustainable alternative. They are defined as preparations of inanimate microorganisms and/or their bioactive components, including short-chain fatty acids, bacteriocins, exopolysaccharides, peptides, and cell

wall fragments. Unlike probiotics, postbiotics offer greater stability, safety, and consistency, making them an effective alternative to AGPs (Zhong et al., 2022).

Postbiotics vs. Probiotics: A Real Competitive Advantage
The probiotics most commonly used in poultry production, such as Lactobacillus spp. and spore-forming Bacillus spp., present certain limitations when compared with postbiotics.

Lactobacillus species are heat-sensitive microorganisms; therefore, their survival during feed pelleting and storage may be compromised. In addition, factors such as chlorination of drinking water can reduce their viability and, consequently, their biological efficacy.

In contrast, Bacillus spp. exhibit high resistance to elevated temperatures due to spore formation. However, their beneficial effects may depend on successful intestinal germination and on the physiological and microbiological conditions of the host. Furthermore, these bacteria do not permanently colonize the gastrointestinal tract, meaning that their biological impact may depend on continuous administration through feed or drinking water.

Postbiotics exhibit high stability during feed processing and storage, as well as in chlorinated drinking water, because they do not rely on cell viability. Moreover, their bioactive compounds can exert their effects immediately upon ingestion, without requiring germination or intestinal colonization. This allows for a faster, more reproducible, and more consistent response (De Marco et al., 2018).

FermNutral: Bioactive Profile of a Full-Spectrum Postbiotic
FermNutral is a postbiotic developed and manufactured by CPBIO through the controlled biological fermentation of the Clostridium butyricum CPBIO3000 strain using natural raw materials. (Figure1)

The product is supplied as granules with demonstrated stability at temperatures exceeding 80°C (simulating the feed pelleting process). The recommended inclusion rate for poultry is 300–500 g/t of feed. FermNutral is produced under FAMI-QS, FDA-cGMP, and ISO 9001/14001/18001 certifications, which have been maintained since 2001.

FermNutral contains a diverse range of bioactive compounds generated during the fermentation process, including teichoic acids, lipoteichoic acids, butyricin, antimicrobial peptides, and exopolysaccharides.

Within its short-chain fatty acid (SCFA) fraction, butyric acid represents approximately 40% of the total SCFAs. Other SCFAs are present at lower concentrations, including acetic acid (21.6 mg/kg) and propionic acid (81.6 mg/kg).
The vitamin fraction includes vitamin E (13.9 IU/kg), vitamin B1 (17.2 mg/kg), vitamin B2 (5.08 mg/kg), vitamin B5 (57.3 mg/kg), vitamin B6 (98.3 mg/kg), vitamin B12 (0.34 mg/kg), folic acid (30.9 mg/kg), and vitamin K3 (1.97 mg/kg). The mineral profile provides calcium (15.2%), total phosphorus (0.76%), iron (760 mg/kg), zinc (42 mg/kg), magnesium (3,600 mg/kg), and chromium (11.67 mg/kg). Additionally, FermNutral contains 17 amino acids, including glutamic acid (1.37%), alanine (0.59%), valine (0.46%), leucine (0.50%), and lysine (0.29%). Altogether all amino acids are between 10-12% in product.

This unique combination of bioactive metabolites, nutrients, vitamins, minerals, and amino acids supports intestinal integrity, microbial balance, immune function, and productive performance in poultry.

Figure 1: A postbiotic product derived from biological fermentation of Clostridium butyricum CPBIO3000 using natural raw materials

FermNutral: Bioactive Compounds
FermNutral contains a wide range of bioactive compounds generated during the fermentation process, with butyric acid being the predominant short-chain fatty acid (SCFA), representing approximately 40% of the product. Butyrate serves as a major energy source for enterocytes and promotes epithelial renewal, mucin synthesis, and the expression of tight junction proteins. These effects contribute to maintaining intestinal barrier integrity and reducing intestinal permeability.
In addition, butyrate exhibits immunomodulatory and anti-inflammatory properties through its ability to regulate epigenetic processes, promote goblet cell differentiation, and stimulate the activation of regulatory T lymphocytes. It may also enhance intestinal serotonin release, which has been associated with the gut-brain axis and productive performance. Acetic and propionic acids complement these effects by regulating the intestinal environment and inhibiting undesirable microorganisms.

FermNutral also provides teichoic acids and lipoteichoic acids, which are recognized by Toll-like receptor 2 (TLR-2) on the intestinal mucosa. These components modulate both innate and adaptive immune responses, promoting a balance between immune defense and tolerance while helping to control intestinal inflammation (Pasquina et al., 2013; Muhammad et al., 2021).

Furthermore, FermNutral supplies butyricin (a bacteriocin), bioactive peptides, and antimicrobial peptides produced during fermentation, which contribute to the control of undesirable microorganisms and the modulation of intestinal microbiota. Exopolysaccharides are also present and have been reported to stimulate secretory IgA production and strengthen the mucosal barrier. In addition, the product’s vitamin and mineral profile acts synergistically to support immune function, antioxidant status, intestinal integrity, and productive performance.

FermNutral in poultry production
Several experiments conducted in China and Thailand have demonstrated the efficacy of FermNutral in poultry production. In a study at Guizhou University (China) comparing a control diet with additives such as FermNutral, Clostridium butyricum, protected sodium butyrate, and tributyrin in broiler chickens, the postbiotic (FermNutral) was confirmed to improve weight gain (+13%) and reduce feed conversion ratio (-11.68%) compared with the control and other experimental treatments.

In addition, another experiment carried out in a commercial broiler farm in China found that FermNutral reduced the feed conversion ratio (1.73 vs 1.77) and improved viability (+1.94) and the European Production Efficiency Factor (EPEF; 338.70 vs 315.30) in relation to the control diet.
Likewise, in a commercial broiler farm in Thailand, the use of FermNutral increased weight gain (+4.2%) and EPEF (+11.70%) and reduced feed conversion ratio (-7.69%). Furthermore, other trials conducted at Guizhou University (China) showed that FermNutral increased villus height in the duodenum (+9%), jejunum (+4%), and ileum (+8%), and improved the villus height to crypt depth ratio (V/C) in the duodenum (6.92 vs 6.27) and jejunum (5.71 vs 5.04).

Figure 3 : FermNutral effect on Immunoglobulins

Additional results from this experiment reported that FermNutral decreased the population of Escherichia coli in the duodenum (0.014 vs 0.234) and jejunum (0.0004 vs 0.013). Moreover, it promoted the growth of Lactobacillus in different intestinal segments, as determined by the relative abundance of microorganisms through 16S rDNA sequencing. (Figure 2) Finally, the inclusion of FermNutral in the diet improved the concentration of IgA (+13%), IgG (+19%), and IgM (+24%) compared with the control diet. (Figure 3)

Figure 2 : 16S rDNA sequencing to determine relative abundance of microorganisms in Poultry Intestine

Other trials conducted on a commercial farm in China with 48-week-old laying hens showed that FermNutral improved laying rate (+1.4) and shell thickness (+0.05 mm), while reducing feed conversion ratio (-0.06) and broken eggs (-2.6%), without affecting other productive performance parameters.

Likewise, in an experiment carried out at Henan Agricultural University, China, using 50-week-old laying hens, FermNutral increased egg weight (61.63 vs 59.77 vs g) and improved feed conversion ratio (2.08 vs 2.11 vs), while reducing dirty eggs (0.17 vs 0.45 %), broken eggs (0.32 vs 0.47 %), and unfit eggs (0.15 vs 0.28 %). These results demonstrate that FermNutral is an innovative and differentiated alternative within the new generation of postbiotics.

References
De Marco S, et al. (2018). Probiotic cell-free supernatants exhibit anti-inflammatory and antioxidant activity. Evidence-Based Complementary and Alternative Medicine.
Liu H, et al. (2023). Postbiotics modulate gut health and laying performance in laying hens. Animal Nutrition, 14, 244–256.
Muhammad I, et al. (2021). Lipoteichoic acid from Bacillus subtilis improves immune function of broiler chickens. Antioxidants, 10(9), 1414.
Pasquina LW, et al. (2013). Teichoic acid biosynthesis as an antibiotic target. Current Opinion in Microbiology, 16(5), 531–537.
Zhong R, et al. (2022). Gut microbiota and its interactions with postbiotics in animal production. Frontiers in Microbiology, 13, 831495.
About CPBIO – A Global Biotech Company, Based on the global practice of Charoen Pokphand Group in the agricultural, animal husbandry and food industry chain, CPBIO has extensively and deeply participated in the health cause of animals, the earth and human beings with the thinking of the whole industry chain. Organizations and individuals in large-scale validated products and solutions.

About CPBIO – A Global Biotech Company, Based on the global practice of Charoen Pokphand Group in the agricultural, animal husbandry and food industry chain, CPBIO has extensively and deeply participated in the health cause of animals, the earth and human beings with the thinking of the whole industry chain. Organizations and individuals in large-scale validated products and solutions.

The 27th edition of World Poultry Congress (WPC) 2026 organised by the World’s Poultry Science Association (WPSA) at the Metro Toronto Convention Centre, Toronto, Canada, from July 13–17, 2026 was recognised as the world’s premier gathering for poultry science and technology, WPC 2026 had brought together a good delegates comprising poultry scientists, researchers, academicians, veterinarians, industry leaders, production specialists, policymakers, and students from more than 85 countries. The congress served as an exceptional platform for exchanging knowledge, showcasing cutting-edge innovations and strengthening international collaborations that will shape the future of the poultry industry.

The scientific and technical program covered a wide spectrum of critical topics including genetics and breeding, poultry nutrition, health and disease prevention, animal welfare, sustainability, precision production technologies, processing innovations and global food security. At a time when the poultry sector is addressing evolving challenges related to disease management, climate resilience, sustainability and feeding a growing global population, forums like WPC continue to play a pivotal role in driving science-based solutions and technological advancement.

Held once every four years under the auspices of the World’s Poultry Science Association (WPSA), the World Poultry Congress remains one of the most influential international platforms dedicated to advancing poultry science and industry worldwide.

The success of WPC 2026 was made possible through the support of leading global organizations, including Elanco and Cargill Animal Nutrition and Health as Platinum Sponsors, Merck Animal Health and Zoetis as Gold Sponsors, Anitox, Evonik, Novus International, Inc, Huvepharma; Trouw Nutrition, Novonesis Animal Health and Nutrition, Nor-Feed, Insighter Biotechnology, JBT Marel, Adisseo, Jefo Biotechnology, Olmix Biotechnology Research and Vtagro as Bronze Sponsors and was supported by Jamesway, Hendrix Genetics Layers, Egg Farmers of Canada, Chicken Farmers of Canada, Turkey Farmers of Canada, Canadian Hatching Egg Producers, Alternative Design Manufacturing and Suply, Inc., Allix3, US-RSPE, JRS Livestock Applications and Hy-line International. WPC-2016 was further supported by esteemed media partners including Canadian Poultry Magazine, WATT Poultry, Agri Insight, Poultry Creations, Gulf Poultry, Modern Poultry, and aviNews International.

The exhibitors displayed their promotional material in Exhibit Hall and the seminars / presentations were in various session rooms. The poster and oral presentation sessions represented the cutting edge of global poultry research. Forty plus speakers from six continents, hundreds of abstracts across every major area of poultry science. During World Poultry Congress 2026, it was my privilege to meet distinguished poultry leaders, scientists, researchers, innovators and industry colleagues from around the world and explored new opportunities for collaboration that will contribute to the sustainable growth and future of the global poultry sector.

My sincere congratulations to the World’s Poultry Science Association (WPSA), the organising committee, sponsors, exhibitors, and everyone who worked tirelessly to make WPC 2026 an outstanding success.As one memorable chapter comes to an end, we now look forward to the 28th World Poultry Congress, which will be held in Tokyo, Japan, from July 21–25, 2030.

Introduction : Every year, invisible contaminants hidden within grains and feed ingredients silently reduce livestock productivity. Mycotoxins—naturally occurring toxic compounds produced by fungi—are responsible for millions of dollars in economic losses through poor growth, reduced immunity, reproductive disorders, lower feed efficiency, and increased mortality. Although impossible to see with the naked eye, their impact on poultry, swine, and dairy production is enormous.

What Are Mycotoxins?
Mycotoxins are toxic secondary metabolites produced by moulds such as Aspergillus, Fusarium, and Penicillium. Scientists have identified over 300 different mycotoxins, and studies indicate that nearly one-quarter of global feed supplies may be contaminated.
The most economically important toxins include:
-Aflatoxins
– Ochratoxins
– Fumonisins
– Deoxynivalenol (DON)
– T-2 Toxin
– Zearalenone
Each affects animals differently, but all reduce productivity and profitability.

Why Do Mycotoxins Develop?
Moulds flourish when four conditions come together:
– Warm temperatures
– High humidity
– Moisture in grains
– Oxygen
Once established, fungal growth continues during harvesting, storage, transportation, and feed manufacturing unless properly controlled.

India’s Mycotoxin Challenge
Recent testing presented in the report paints a worrying picture. 6,304 feed analysis, 99% contamination, and 83% above the performance-risk threshold.
Key Findings

– 6,304 feed analysis conducted
– 99% showed detectable contamination
– 83% exceeded performance-risk thresholds
Among ingredients, DORB, peanut meal, maize, soybean meal, DDGS, and corn gluten all showed significant contamination levels.

Multiple Mycotoxins: A Greater Threat
Animals are rarely exposed to a single toxin.
Instead, feeds commonly contain multiple mycotoxins that interact synergistically, making the combined damage significantly greater than the effect of individual toxins. This explains why even relatively low toxin concentrations can cause substantial production losses.

Economic Impact on Farms
The consequences are visible across every production system.

Poultry
– Lower feed intake
– Reduced weight gain
– Poor feed conversion
– Thin eggshells
– Lower hatchability
– Fatty liver
– Weak immunity

Swine
– Reproductive disorders
– Embryonic mortality
– Vomiting
– Reduced growth
– Feed refusal
– Tail necrosis
– Liver and kidney damage
Ultimately, these problems translate directly into economic losses through poorer animal performance.

The Hidden Cost: Immune Suppression
– One of the most damaging effects of mycotoxins is their ability to suppress the immune system.
– Animals become more vulnerable to bacterial and viral infections while showing reduced responses to vaccines and treatments.
– This means disease outbreaks become more severe and recovery becomes slower.

Can Nutrition Help?
Nutritional interventions can reduce the impact of toxins.

Recommended approaches include:
– Higher amino acid supplementation
– Vitamins E, C, and D3
– Selenium
– Choline chloride
– Liver-support products
– Mold inhibitors
– Broad-spectrum toxin binders
These measures improve resilience while reducing toxin damage.

Scientific Toxin Elimination Management (STEM-500)
An effective strategy combines four complementary actions:
1. Prevention
Prevent fungal growth before toxins develop.
2. Elimination
Bind multiple mycotoxins irreversibly.
3. Neutralization
Use enzymatic systems to neutralize toxins.
4. Gut Ecology Enhancement
Improve gut health while strengthening immunity and reducing pathogen pressure. This integrated approach offers broader protection than relying on toxin binders alone.

Featured Solution: STEM-500
The presentation introduces STEM-500, a multi-component toxin management product formulated with:
– Specially treated HSCAS
– Organic acids
– Oxine Copper
– MOS
– Bio-active phytocompounds
– Polyphenols
– Lactobacillus
– Lipotropic agents
According to the presentation, the product is designed to reduce mould growth, bind multiple mycotoxins, minimize endotoxin effects, improve liver function, support gut health, and enhance feed conversion, growth, and survival.

Conclusion
Mycotoxins remain one of the most significant hidden threats in modern animal production. Since contamination can occur throughout the grain supply chain, prevention alone is rarely sufficient. A comprehensive management strategy—combining mould control, toxin binding, detoxification, and gut health support—is essential for maintaining animal health and maximizing production efficiency.

Biosecurity as an Investment: Why Disease Prevention delivers the Best Return on Investment (ROI) in Poultry Production

Prof. (Dr.) P.K. Shukla and Dr. Amitav Bhattacharyya
Department of Poultry Science, College of Veterinary Science and
Animal Husbandry, Mathura- 281001 (U.P.)

Introduction
Over the last five decades, the poultry industry has undergone a remarkable transformation. Scientific advances in genetics, nutrition, housing, disease control, and management have enabled producers to achieve unprecedented levels of productivity. Poultry meat and eggs have become among the most affordable and nutritious sources of animal protein, making the industry indispensable for global food and nutritional security. In India, poultry production has developed into an important agribusiness sector, generating employment for millions of people while supporting allied industries such as hatcheries, feed manufacturing, pharmaceuticals, processing, transportation, and retail.

Despite these achievements, infectious diseases remain one of the greatest constraints to sustainable poultry production. Diseases such as avian influenza, Newcastle disease, infectious bronchitis, infectious bursal disease, Marek’s disease, coccidiosis, salmonellosis, and mycoplasmosis continue to cause substantial economic losses. These diseases not only reduce flock productivity but also affect food safety, consumer confidence, international trade, and public health.

Under modern intensive production systems, disease outbreaks spread rapidly because of high stocking densities, frequent movement of birds and equipment, and increasing interactions among farms. Once pathogens establish themselves within a flock, economic losses accumulate through mortality, reduced growth, poor feed conversion, lower egg production, treatment expenses, and market disruptions. Consequently, preventing disease introduction is far more economical than managing disease after it has occurred.

Biosecurity has therefore become the foundation of modern poultry health management. It is no longer viewed merely as a collection of hygiene practices but as a comprehensive risk management strategy designed to prevent disease while maximizing productivity and profitability.

Economic Impact of Poultry Diseases
The financial consequences of poultry diseases extend far beyond mortality alone. Disease outbreaks affect every component of the production chain, from breeder farms and hatcheries to processing plants, retailers, and consumers.

Direct economic losses include increased mortality, poor weight gain, reduced egg production, inferior feed conversion efficiency, decreased hatchability, veterinary expenses, medication costs, diagnostic testing, and emergency vaccination programmes. Even mild infections that do not cause obvious mortality often reduce flock performance sufficiently to eliminate expected profit margins.

Indirect losses are frequently even greater. Disease outbreaks can result in movement restrictions, export bans, lower consumer demand, reduced processing efficiency, insurance costs, and disruption of supply chains. Highly pathogenic avian influenza has repeatedly demonstrated how a single outbreak can result in massive financial losses through depopulation, compensation payments, and trade restrictions.
Equally damaging are the hidden costs associated with subclinical infections. Chronic disease reduces flock uniformity, suppresses immune responses, increases susceptibility to secondary infections, and diminishes reproductive performance without producing dramatic clinical signs. Such losses often remain unnoticed but continuously erode farm profitability.
These economic realities highlight an important principle: disease prevention should not be regarded solely as a veterinary responsibility but as an essential business strategy that protects investments in chicks, feed, labour, housing, equipment, and marketing.

Prevention Versus Treatment: The Economics of Biosecurity
The principle that “prevention is better than cure” has special relevance in commercial poultry production. Intensive poultry systems house thousands of genetically similar birds in close proximity, allowing infectious agents to spread extremely rapidly once introduced.

By the time clinical signs become evident, pathogens have often multiplied extensively within the flock and contaminated the surrounding environment. Even if treatment successfully controls mortality, birds rarely regain their original production potential. Reduced feed efficiency, slower growth, delayed marketing age, poor egg production, and increased susceptibility to secondary infections frequently persist throughout the production cycle.
Treatment also involves considerable expenditure on antibiotics, supportive medications, laboratory investigations, veterinary consultation, and labour. These costs are incurred after production losses have already begun, thereby reducing overall profitability.
Biosecurity interrupts pathogen transmission before infection becomes established. Investments in perimeter fencing, controlled farm access, sanitation, water treatment, pest management, employee training, and visitor control substantially reduce the probability of disease introduction. Unlike treatment costs, preventive investments continue generating economic returns throughout successive production cycles by maintaining flock health and preserving production efficiency.
Numerous studies have shown that the cost of implementing effective biosecurity programmes is significantly lower than the cumulative losses associated with disease outbreaks. Consequently, biosecurity functions as a form of biological insurance that safeguards every other investment made in poultry production.

Principles of Poultry Biosecurity
Biosecurity is a science-based management system aimed at preventing the introduction, establishment, and spread of infectious agents. Effective biosecurity requires an integrated approach involving infrastructure, operational procedures, personnel behaviour, environmental sanitation, and continuous monitoring.
Three fundamental principles form the basis of poultry biosecurity:

Bio-exclusion focuses on preventing pathogens from entering the farm through controlled access, procurement of healthy chicks, vehicle disinfection, quarantine, and visitor management.

Bio-containment prevents infectious agents from spreading outside infected premises by implementing movement restrictions, proper disposal of carcasses and litter, and thorough cleaning and disinfection.

Bio-management minimizes disease pressure within the farm through vaccination, optimal nutrition, environmental management, pest control, water sanitation, litter management, and animal welfare practices.

Farm design also plays an important role in disease prevention. Poultry farms should be located away from other commercial farms, live bird markets, and migratory bird habitats. Clearly defined clean and dirty zones, all-in/all-out production systems, and adequate downtime between flocks reduce pathogen survival and transmission.
Personnel hygiene is equally critical. Farm workers should use dedicated clothing and footwear, maintain hand hygiene, comply with visitor restrictions, and receive regular biosecurity training. Similarly, feed and water must be protected from contamination through proper storage, water chlorination, and routine quality monitoring.
Rodent and insect control programmes, together with scientifically approved mortality disposal methods, further strengthen disease prevention by eliminating important sources of pathogen transmission.

Biosecurity as a Strategic Business Investment
Historically, many poultry producers regarded expenditures on sanitation, fencing, disinfection equipment, employee training, and surveillance as unavoidable operating costs. Modern poultry enterprises increasingly recognize that these expenditures are investments that protect all other farm assets.

Feed represents nearly two-thirds of total production costs. Healthy birds utilize feed more efficiently, grow faster, produce more eggs, and require fewer medications than diseased birds. Even modest improvements in feed conversion ratio can substantially increase profitability.
Strong biosecurity systems also improve market confidence. Consumers increasingly demand poultry products that are safe, traceable, and produced under high standards of animal health and welfare. Farms maintaining effective biosecurity programmes are better positioned to comply with certification schemes, quality assurance standards, and export requirements.
From a business perspective, biosecurity reduces biological risk while improving enterprise resilience. Disease outbreaks can rapidly destroy years of investment in genetics, housing, labour, and marketing. Preventive biosecurity therefore serves as a protective framework that preserves productivity, enhances competitiveness, and ensures long-term sustainability.
Modern poultry producers should therefore ask not whether they can afford to invest in biosecurity, but whether they can afford the consequences of inadequate disease prevention.

Practical Biosecurity Measures that Enhance Profitability
The success of any biosecurity programme depends on its consistent implementation at the farm level. While sophisticated infrastructure and advanced technologies can strengthen disease prevention, many highly effective biosecurity interventions are simple, practical, and relatively inexpensive. Their value lies not in high capital investment but in disciplined and continuous application.

The first line of defence is strict farm access control. Entry to poultry houses should be restricted to essential personnel, and all visitors should comply with hygiene protocols including hand sanitization, use of dedicated clothing and boots, and passage through properly maintained footbaths. Maintaining visitor records and enforcing a minimum downtime for personnel who have recently visited other poultry farms significantly reduce the likelihood of introducing infectious pathogens.
Cleaning and disinfection remain the cornerstone of disease prevention. Poultry houses, equipment, feeders, drinkers, egg trays, transport crates, and vehicles should be thoroughly cleaned to remove organic matter before applying appropriate disinfectants. Adequate downtime between production cycles allows environmental pathogen loads to decline naturally and improves the effectiveness of sanitation programmes.
Feed and water hygiene are equally important because they represent continuous sources of pathogen exposure. Feed should be procured from reliable manufacturers and stored under dry, rodent-proof conditions to prevent fungal contamination and mycotoxin development.
Drinking water should be regularly tested for microbial quality, chlorinated when necessary, and supplied through cleaned pipelines to minimize biofilm formation.
Integrated pest management also plays a critical role. Rodents, flies, beetles, mosquitoes, and wild birds serve as mechanical carriers of numerous bacterial and viral pathogens. Effective pest control, combined with scientific carcass disposal methods such as composting, rendering, or incineration, minimizes environmental contamination and pathogen persistence.
Finally, employee education is perhaps the most cost-effective biosecurity investment. Every worker should understand disease transmission pathways, recognize early clinical signs, and consistently follow standard operating procedures (SOPs). A well-trained workforce transforms biosecurity from a written protocol into a daily management culture that protects flock health and farm profitability.

Digital Transformation of Poultry Biosecurity
Rapid advances in digital technologies are revolutionizing poultry health management by shifting disease control from a reactive to a predictive approach. Precision livestock farming integrates artificial intelligence (AI), machine learning, sensor technologies, automation, and molecular diagnostics to improve disease surveillance and decision-making.

Artificial intelligence can analyse production data such as feed intake, water consumption, mortality, growth rate, and behavioural changes to detect early indicators of disease before clinical signs become apparent. Such predictive systems enable farmers to intervene promptly, thereby reducing mortality and economic losses.
The Internet of Things (IoT) has further strengthened biosecurity by enabling continuous monitoring of environmental variables including temperature, humidity, ammonia concentration, carbon dioxide, ventilation efficiency, and water quality. Automated alerts help managers respond immediately to deviations that may compromise bird health.
Computer vision systems are increasingly being used to monitor flock behaviour, feeding activity, movement patterns, and gait abnormalities. These technologies allow rapid identification of subtle behavioural changes associated with disease onset.
Molecular diagnostic tools such as polymerase chain reaction (PCR), real-time PCR, and genomic sequencing permit rapid detection of viral, bacterial, and parasitic pathogens, facilitating timely intervention. Blockchain-based traceability systems and cloud-based farm management platforms further enhance transparency, certification, and supply chain confidence.
Although digital biosecurity requires initial investment, its long-term benefits include reduced disease incidence, improved productivity, lower veterinary costs, enhanced decision-making, and increased resilience against emerging diseases.

Biosecurity Challenges and Opportunities in India
India has become one of the world’s leading producers of poultry meat and eggs, yet the country’s diverse production systems create unique biosecurity challenges. Large integrated commercial operations coexist with smallholder and backyard poultry farms, creating epidemiological interfaces that facilitate pathogen transmission.

One of the major constraints is uneven awareness regarding the economic importance of biosecurity. Large poultry companies generally maintain comprehensive disease prevention programmes, whereas many small and medium-scale producers continue to regard biosecurity as an additional expense rather than a productive investment. Financial limitations often prevent investment in essential infrastructure such as perimeter fencing, vehicle disinfection facilities, controlled farm entry, and scientific carcass disposal systems.
High poultry density in several production clusters further increases disease risk. Frequent movement of day-old chicks, feed, eggs, live birds, and farm personnel across states facilitates pathogen dissemination. Backyard poultry, live bird markets, and mixed farming systems involving ducks and other livestock also increase the risk of zoonotic disease transmission.
Despite these challenges, India possesses significant opportunities to strengthen poultry biosecurity. The country has a strong network of veterinary universities, diagnostic laboratories, research institutes, extension agencies, and progressive poultry companies capable of promoting scientific disease prevention. Government initiatives supporting livestock health, antimicrobial stewardship, digital agriculture, and the One Health approach can further accelerate adoption of comprehensive biosecurity practices.
Public-private partnerships involving industry associations, academic institutions, pharmaceutical companies, and producer organizations will be instrumental in developing practical, affordable, and scalable biosecurity solutions for Indian poultry farmers.

Biosecurity within the One Health Framework
Modern biosecurity extends beyond farm profitability to encompass animal health, public health, and environmental sustainability. The One Health concept recognizes the close interdependence of humans, animals, and ecosystems.

Effective poultry biosecurity reduces the circulation of zoonotic pathogens such as avian influenza and Salmonella, thereby protecting consumers, farm workers, and surrounding communities. Healthy flocks also require fewer therapeutic antibiotics, contributing to global efforts to combat antimicrobial resistance (AMR).
Good biosecurity practices improve waste management, reduce contamination of soil and water resources, and minimize environmental dissemination of infectious agents. Consequently, investments in poultry biosecurity generate societal benefits that extend far beyond individual farms by supporting food safety, environmental protection, and national food security.

Capacity Building and Policy Support
Infrastructure alone cannot guarantee successful biosecurity. Human behaviour remains one of the most critical determinants of disease prevention. Continuous training programmes should therefore be provided for farm owners, managers, veterinarians, technicians, and workers on disease recognition, personal hygiene, vaccination, cleaning and disinfection, pest control, mortality management, and emergency response.
Routine biosecurity audits, risk assessments, and comprehensive record-keeping systems enable producers to monitor flock performance and identify weaknesses requiring corrective action. Standard operating procedures should be regularly reviewed and updated in response to emerging disease threats and technological developments.
Government agencies also have an essential role in strengthening national biosecurity through veterinary services, laboratory networks, surveillance systems, science-based regulations, and financial incentives that encourage producers to invest in preventive infrastructure. Harmonization of national standards with international guidelines will further improve India’s competitiveness in global poultry trade.

Way Forward
Biosecurity has evolved from a routine veterinary recommendation into one of the most valuable strategic investments in modern poultry production. Scientific evidence consistently demonstrates that prevention delivers substantially greater economic returns than treatment. Every investment made in disease prevention safeguards valuable biological assets, preserves productivity, reduces veterinary expenditure, minimizes antimicrobial use, and enhances market confidence.
For India, where poultry production continues to expand rapidly, widespread adoption of comprehensive biosecurity systems will be fundamental to sustainable growth. Success will require coordinated efforts involving producers, veterinarians, researchers, policymakers, industry organizations, and technology providers working within a One Health framework.
The future of poultry farming will increasingly depend on predictive health management supported by digital technologies, precision farming, artificial intelligence, and robust surveillance systems. Producers who integrate biosecurity into their core business strategy will be better equipped to withstand emerging disease threats, satisfy evolving consumer expectations, and compete successfully in international markets.
Ultimately, the most profitable poultry enterprise is not the one that spends the least on disease prevention, but the one that invests wisely to ensure disease never compromises productivity. Biosecurity should therefore be regarded not as an operational expense but as a high-return investment that protects animal health, public health, environmental sustainability, and the long-term resilience of the poultry industry.

Selected References
1. Alexander, D. J. (2007). An overview of the epidemiology of avian influenza. Vaccine, 25, 5637–5644.
2. FAO. (2023). Good Practices for Biosecurity in the Poultry Sector. Food and Agriculture Organization of the United Nations.
3. Gelaude, P., Schlepers, M., Verlinden, M., et al. (2014). Measuring on-farm poultry biosecurity using Biocheck.UGent. Poultry Science, 93, 2740–2750.
4. Glisson, J. R., Hofacre, C. L., & Christensen, J. P. (2019). Poultry Diseases. Elsevier.
5. WOAH. (2023). Terrestrial Animal Health Code.
6. Swayne, D. E. (Ed.). (2020). Diseases of Poultry (14th ed.). Wiley-Blackwell.
7. World Health Organization. (2022). One Health Joint Plan of Action (2022–2026).
8. World Bank. (2022). One Health Operational Framework for Strengthening Animal Health Systems.
9. FAO. (2022). Biosecurity Guide for Poultry Production and Value Chains.
10. USDA APHIS. (2023). Defend the Flock: Biosecurity for Poultry Owners.